Fluticasone Impurity 8

Name: Fluticasone Impurity 8
Brand: Vaqora Chemicals
SKU: VQ-030845

About Fluticasone Impurity 8

Vaqora Chemicals supplies Fluticasone Impurity 8, an impurity of Fluticasone registered under CAS number 80473-92-3. Its molecular formula is C21H26F2O4S and its molecular weight is 412.5 g/mol. It is also known as Fluticasone Impurity 32.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Fluticasone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Fluticasone Impurity 8 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Fluticasone

View every impurity, metabolite and intermediate we list for Fluticasone.

Fluticasone impurities

Specifications & identifiers

Chemical identifiers
Product name	Fluticasone Impurity 8
Catalogue No.	VQ-030845
CAS Number	80473-92-3
IUPAC name	(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carbothioic S-acid
Molecular formula	C₂₁H₂₆F₂O₄S
Molecular weight	412.5 g/mol
Exact mass	412.152
Grade	Reference Standard
HSN code	38229090
InChIKey	GLAJUXBOZSWZMM-IDIDPBNYSA-N
SMILES	C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)S)O)C)O)F)C)F
PubChem CID	10024665

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	3 / 7
TPSA	75.6 Å²
Synonyms	6a,9a-Difluoro-11b,17a-dihydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17b-carbothioic acid, Fluticasone Impurity 32, 6a,9a-Difluoro-11b,17a-dihydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17a-carbothioic Acid, Androsta-1,4-diene-17-carbothioic Acid, 6,9-difluoro-11,17-d, 6a9a-Difluoro-11b17a-dihydroxy-16a-methyl-3-oxoandrosta-14-diene-17b-carbothioic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H317May cause an allergic skin reaction
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P261, P272, P273, P280, P302 + P352, P321, P333 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Fluticasone Impurity 8?

The CAS Registry Number of Fluticasone Impurity 8 is 80473-92-3. It is also known as 6a,9a-Difluoro-11b,17a-dihydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17b-carbothioic acid, Fluticasone Impurity 32, 6a,9a-Difluoro-11b,17a-dihydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17a-carbothioic Acid.

What is the molecular formula and molecular weight of Fluticasone Impurity 8?

Fluticasone Impurity 8 has the molecular formula C21H26F2O4S and a molecular weight of 412.5 g/mol.

What is Fluticasone Impurity 8 used for?

Fluticasone Impurity 8 is supplied as a characterised reference material related to Fluticasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Fluticasone Impurity 8 can I order?

We supply Fluticasone Impurity 8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Fluticasone Impurity 8?

Yes. Every lot of Fluticasone Impurity 8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Fluticasone Impurity 8 be shipped internationally?

Yes. Fluticasone Impurity 8 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.