8-Hydroxyacyclovir

Name: 8-Hydroxyacyclovir
Brand: Vaqora Chemicals
SKU: VQ-013176

About 8-Hydroxyacyclovir

Listed under CAS 80685-23-0, 8-Hydroxyacyclovir is a process intermediate or related compound of Acyclovir available from Vaqora Chemicals. Formula C8H11N5O4, molecular weight 241.2 g/mol. Its systematic (IUPAC) name is 2-amino-9-(2-hydroxyethoxymethyl)-1,7-dihydropurine-6,8-dione. Alternative names: 8-Hydroxy-9-(2-hydroxyethoxymethyl)guanine and 8-OHACV.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Process chemists and analysts use it when developing synthetic routes to Acyclovir, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 8-Hydroxyacyclovir in 10 mg and 25 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Acyclovir

View every impurity, metabolite and intermediate we list for Acyclovir.

Acyclovir impurities

Specifications & identifiers

Chemical identifiers
Product name	8-Hydroxyacyclovir
Catalogue No.	VQ-013176
CAS Number	80685-23-0
IUPAC name	2-amino-9-(2-hydroxyethoxymethyl)-1,7-dihydropurine-6,8-dione
Molecular formula	C₈H₁₁N₅O₄
Molecular weight	241.2 g/mol
Exact mass	241.0811
Grade	Reference Standard
HSN code	2933
InChIKey	PTSDSAPWOJZBNX-UHFFFAOYSA-N
SMILES	C(COCN1C2=C(C(=O)NC(=N2)N)NC1=O)O
PubChem CID	135530051

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.8
H-bond donors / acceptors	4 / 5
TPSA	129 Å²
Synonyms	2-Amino-7,9-dihydro-9-[(2-hydroxyethoxy)methyl]-1H-purine-6,8-dione, 8-Hydroxy-9-(2-hydroxyethoxymethyl)guanine, 1H-Purine-6,8-dione, 2-amino-7,9-dihydro-9-((2-hydroxyethoxy)methyl)-, 2-amino-8-hydroxy-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one, 2-amino-8-hydroxy-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-1H-purin-6-one, 2-amino-8-hydroxy-9-((2-hydroxyethoxy)methyl)-1,9-dihydro-6H-purin-6-one, 8-OHACV, 8-Hydroxyacyclovir (8-OH-ACV), 9-[(2-Hydroxyethoxy)methyl]-2-imino-3,9-dihydro-2H-purine-6,8-diol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 8-Hydroxyacyclovir?

The CAS Registry Number of 8-Hydroxyacyclovir is 80685-23-0. It is also known as 2-Amino-7,9-dihydro-9-[(2-hydroxyethoxy)methyl]-1H-purine-6,8-dione, 8-Hydroxy-9-(2-hydroxyethoxymethyl)guanine, 1H-Purine-6,8-dione, 2-amino-7,9-dihydro-9-((2-hydroxyethoxy)methyl)-.

What is the molecular formula and molecular weight of 8-Hydroxyacyclovir?

8-Hydroxyacyclovir has the molecular formula C8H11N5O4 and a molecular weight of 241.2 g/mol. Its IUPAC name is 2-amino-9-(2-hydroxyethoxymethyl)-1,7-dihydropurine-6,8-dione.

What is 8-Hydroxyacyclovir used for?

8-Hydroxyacyclovir is supplied as a characterised reference material related to Acyclovir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 8-Hydroxyacyclovir can I order?

We supply 8-Hydroxyacyclovir in Reference Standard grade, in 10 mg, 25 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 8-Hydroxyacyclovir?

Yes. Every lot of 8-Hydroxyacyclovir is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 8-Hydroxyacyclovir be shipped internationally?

Yes. We export 8-Hydroxyacyclovir worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.