4-Bromomethyl-5-methyl-[1,3]dioxol-2-one

Name: 4-Bromomethyl-5-methyl-[1,3]dioxol-2-one
Brand: Vaqora Chemicals
SKU: VQ-049304

About 4-Bromomethyl-5-methyl-[1,3]dioxol-2-one

Vaqora Chemicals supplies 4-Bromomethyl-5-methyl-[1,3]dioxol-2-one, a process intermediate or related compound of Olmesartan registered under CAS number 80715-22-6. The compound has the formula C5H5BrO3, corresponding to a molecular weight of 193.0 g/mol. Common synonyms include 1,3-Dioxol-2-one, 4-(bromomethyl)-5-methyl- and 4-(bromomethyl)-5-methyl-2H-1,3-dioxol-2-one.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Olmesartan, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 4-Bromomethyl-5-methyl-[1,3]dioxol-2-one in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Olmesartan

View every impurity, metabolite and intermediate we list for Olmesartan.

Olmesartan impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Bromomethyl-5-methyl-[1,3]dioxol-2-one
Catalogue No.	VQ-049304
CAS Number	80715-22-6
IUPAC name	4-(bromomethyl)-5-methyl-1,3-dioxol-2-one
Molecular formula	C₅H₅BrO₃
Molecular weight	193 g/mol
Exact mass	191.9422
InChIKey	GWFALVUXAGYMHR-UHFFFAOYSA-N
SMILES	CC1=C(OC(=O)O1)CBr
PubChem CID	10774141

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	0 / 3
TPSA	35.5 Å²
Synonyms	1,3-Dioxol-2-one, 4-(bromomethyl)-5-methyl-, 4-(bromomethyl)-5-methyl-2H-1,3-dioxol-2-one, 4-bromomethyl-5-methyl-1,3-dioxole-2-one, 4-bromomethyl-5-methyl-1,3-dioxo, 1-bromomethyl-2-methylvinylene carbonate, 4-bromomethyl-5-methyl-2-oxo-1,3dioxol, 5-bromomethyl-4-methyl-1,3-dioxol-2-one, 4-bromomethyl-5-methyl-2-oxo-1,3-dioxole, 4-bromomethyl-5-methyl-1,3-dioxolen-2-one, 5-bromomethyl-4-methyl-1,3-dioxolen-2-one

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H227Combustible liquid
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P210, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P370 + P378, P403, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Bromomethyl-5-methyl-[1,3]dioxol-2-one?

The CAS Registry Number of 4-Bromomethyl-5-methyl-[1,3]dioxol-2-one is 80715-22-6. It is also known as 1,3-Dioxol-2-one, 4-(bromomethyl)-5-methyl-, 4-(bromomethyl)-5-methyl-2H-1,3-dioxol-2-one, 4-bromomethyl-5-methyl-1,3-dioxole-2-one.

What is the molecular formula and molecular weight of 4-Bromomethyl-5-methyl-[1,3]dioxol-2-one?

4-Bromomethyl-5-methyl-[1,3]dioxol-2-one has the molecular formula C5H5BrO3 and a molecular weight of 193 g/mol. Its IUPAC name is 4-(bromomethyl)-5-methyl-1,3-dioxol-2-one.

What is 4-Bromomethyl-5-methyl-[1,3]dioxol-2-one used for?

4-Bromomethyl-5-methyl-[1,3]dioxol-2-one is supplied as a characterised reference material related to Olmesartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Bromomethyl-5-methyl-[1,3]dioxol-2-one can I order?

We supply 4-Bromomethyl-5-methyl-[1,3]dioxol-2-one, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Bromomethyl-5-methyl-[1,3]dioxol-2-one?

Yes. Every lot of 4-Bromomethyl-5-methyl-[1,3]dioxol-2-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Bromomethyl-5-methyl-[1,3]dioxol-2-one be shipped internationally?

Yes. 4-Bromomethyl-5-methyl-[1,3]dioxol-2-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.