7-Chloro-4-(4-hydroxyanilino)quinoline

Name: 7-Chloro-4-(4-hydroxyanilino)quinoline
Brand: Vaqora Chemicals
SKU: VQ-021566

About 7-Chloro-4-(4-hydroxyanilino)quinoline

Listed under CAS 81099-86-7, 7-Chloro-4-(4-hydroxyanilino)quinoline is a metabolite or degradation product of Amodiaquine available from Vaqora Chemicals. The compound has the formula C15H11ClN2O, corresponding to a molecular weight of 270.71 g/mol. Systematically, it is named 4-[(7-chloroquinolin-4-yl)amino]phenol. It is also known as 4-((7-Chloroquinolin-4-yl)amino)phenol or 7-Chloro-4-(4-hydroxyphenylamino)quinoline.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Amodiaquine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Amodiaquine

View every impurity, metabolite and intermediate we list for Amodiaquine.

Amodiaquine impurities

Specifications & identifiers

Chemical identifiers
Product name	7-Chloro-4-(4-hydroxyanilino)quinoline
Catalogue No.	VQ-021566
CAS Number	81099-86-7
IUPAC name	4-[(7-chloroquinolin-4-yl)amino]phenol
Molecular formula	C₁₅H₁₁ClN₂O
Molecular weight	270.71 g/mol
Exact mass	270.056
Grade	Reference Standard
HSN code	38229090
InChIKey	FFAVTICKABAMSV-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1NC2=C3C=CC(=CC3=NC=C2)Cl)O
PubChem CID	224178

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	2 / 3
TPSA	45.2 Å²
Synonyms	4-((7-Chloroquinolin-4-yl)amino)phenol, 7-Chloro-4-(4-hydroxyphenylamino)quinoline, 4-[(7-chloro-4-quinolyl)amino]phenol, 4-(7-chloroquinolin-4-ylamino)phenol, CBMicro_029120, Phenol, 4-[(7-chloro-4-quinolinyl)amino]-, GNF-PF-1310, Quinoline, 7-chloro-4-p-hydroxyanilino-, 4-[(7-Chloro-4-quinolinyl)amino]phenol, Phenol, p-[(7-chloro-4-quinolyl)amino]-

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 7-Chloro-4-(4-hydroxyanilino)quinoline?

The CAS Registry Number of 7-Chloro-4-(4-hydroxyanilino)quinoline is 81099-86-7. It is also known as 4-((7-Chloroquinolin-4-yl)amino)phenol, 7-Chloro-4-(4-hydroxyphenylamino)quinoline, 4-[(7-chloro-4-quinolyl)amino]phenol.

What is the molecular formula and molecular weight of 7-Chloro-4-(4-hydroxyanilino)quinoline?

7-Chloro-4-(4-hydroxyanilino)quinoline has the molecular formula C15H11ClN2O and a molecular weight of 270.71 g/mol. Its IUPAC name is 4-[(7-chloroquinolin-4-yl)amino]phenol.

What is 7-Chloro-4-(4-hydroxyanilino)quinoline used for?

7-Chloro-4-(4-hydroxyanilino)quinoline is supplied as a characterised reference material related to Amodiaquine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 7-Chloro-4-(4-hydroxyanilino)quinoline can I order?

We supply 7-Chloro-4-(4-hydroxyanilino)quinoline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 7-Chloro-4-(4-hydroxyanilino)quinoline?

Yes. Every lot of 7-Chloro-4-(4-hydroxyanilino)quinoline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 7-Chloro-4-(4-hydroxyanilino)quinoline be shipped internationally?

Yes. 7-Chloro-4-(4-hydroxyanilino)quinoline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.