Treprostinil

About Treprostinil

Treprostinil is a high-purity reference standard of Treprostinil carrying the CAS registry number 81846-19-7. With the molecular formula C23H34O5, it has a molar mass of 390.5 g/mol. Alternative names: Rumodolin and UT-15.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Treprostinil, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Treprostinil is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Treprostinil

View every impurity, metabolite and intermediate we list for Treprostinil.

Treprostinil impurities

Specifications & identifiers

Chemical identifiers
Product name	Treprostinil
Catalogue No.	VQ-042657
CAS Number	81846-19-7
IUPAC name	2-[[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[g]naphthalen-5-yl]oxy]acetic acid
Molecular formula	C₂₃H₃₄O₅
Molecular weight	390.5 g/mol
Exact mass	390.2406
Grade	Reference Standard
HSN code	38229090
InChIKey	PAJMKGZZBBTTOY-ZFORQUDYSA-N
SMILES	CCCCC[C@@H](CC[C@H]1[C@@H](C[C@H]2[C@@H]1CC3=C(C2)C(=CC=C3)OCC(=O)O)O)O
PubChem CID	6918140

Physical properties
Physical form	Solid
LogP (XLogP3)	4.5
H-bond donors / acceptors	3 / 5
TPSA	87 Å²
Synonyms	Rumodolin, UT-15, LRX-15, Tyvaso dpi, 15-AU-81, trepostinil sodium, Remodulin, Treprostinil free acid, LRX 15, LRX -15, BW 15AU, 81846-19-7 (free acid)

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P262, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P318, P319, P321, P330, P332 + P317, P337 + P317, P361 + P364, P362 + P364, P403 + P233, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Treprostinil?

The CAS Registry Number of Treprostinil is 81846-19-7. It is also known as Rumodolin, UT-15, LRX-15.

What is the molecular formula and molecular weight of Treprostinil?

Treprostinil has the molecular formula C23H34O5 and a molecular weight of 390.5 g/mol. Its IUPAC name is 2-[[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[g]naphthalen-5-yl]oxy]acetic acid.

What is Treprostinil used for?

Treprostinil is supplied as a characterised reference material related to Treprostinil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Treprostinil can I order?

We supply Treprostinil in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Treprostinil?

Yes. Every lot of Treprostinil is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Treprostinil be shipped internationally?

Yes. Treprostinil is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.