Epalrestat

Name: Epalrestat
Brand: Vaqora Chemicals
SKU: VQ-025553

About Epalrestat

Vaqora Chemicals supplies Epalrestat, a high-purity reference standard of Epalrestat registered under CAS number 82159-09-9. With the molecular formula C15H13NO3S2, it has a molar mass of 319.4 g/mol. Systematically, it is named 2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid. It is also known as Ono-2235 or Ono 2235.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Epalrestat standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Epalrestat is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Epalrestat

View every impurity, metabolite and intermediate we list for Epalrestat.

Epalrestat impurities

Specifications & identifiers

Chemical identifiers
Product name	Epalrestat
Catalogue No.	VQ-025553
CAS Number	82159-09-9
IUPAC name	2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid
Molecular formula	C₁₅H₁₃NO₃S₂
Molecular weight	319.4 g/mol
Exact mass	319.0337
Grade	Reference Standard
HSN code	38229090
InChIKey	CHNUOJQWGUIOLD-NFZZJPOKSA-N
SMILES	C/C(=C\C1=CC=CC=C1)/C=C\2/C(=O)N(C(=S)S2)CC(=O)O
PubChem CID	1549120

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	1 / 5
TPSA	115 Å²
Synonyms	Ono-2235, Ono 2235, Aldorin, Tanglin, ONO-2, 5-((1Z,2E)-2-Methyl-3-phenylpropenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic acid, 5-((Z,E)-beta-Methylcinnamylidene)-4-oxo-2-thioxo-3-thiazolidineacetic acid, 3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo-, (E,E)-, 3-carboxymethyl-5-(methyl-3-phenylpropenylidene)rhodanine, 2-((z)-5-((e)-2-methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid, ONO 2, (Z,Z)-5-(2-Methyl-3-phenyl-propenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic Acid

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Epalrestat?

The CAS Registry Number of Epalrestat is 82159-09-9. It is also known as Ono-2235, Ono 2235, Aldorin.

What is the molecular formula and molecular weight of Epalrestat?

Epalrestat has the molecular formula C15H13NO3S2 and a molecular weight of 319.4 g/mol. Its IUPAC name is 2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid.

What is Epalrestat used for?

Epalrestat is supplied as a characterised reference material related to Epalrestat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Epalrestat can I order?

We supply Epalrestat in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Epalrestat?

Yes. Every lot of Epalrestat is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Epalrestat be shipped internationally?

Yes. Epalrestat is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.