2-Methyl-2-phenylpropanoic acid

Name: 2-Methyl-2-phenylpropanoic acid
Brand: Vaqora Chemicals
SKU: VQ-029477

About 2-Methyl-2-phenylpropanoic acid

Vaqora Chemicals supplies 2-Methyl-2-phenylpropanoic acid, an impurity of Bosentan registered under CAS number 826-55-1. Its molecular formula is C10H12O2 and its molecular weight is 164.2 g/mol. It is also known as 2-Phenylisobutyric Acid or alpha,alpha-DIMETHYLPHENYLACETIC ACID.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Bosentan, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 2-Methyl-2-phenylpropanoic acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Bosentan

View every impurity, metabolite and intermediate we list for Bosentan.

Bosentan impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Methyl-2-phenylpropanoic acid
Catalogue No.	VQ-029477
CAS Number	826-55-1
IUPAC name	2-methyl-2-phenylpropanoic acid
Molecular formula	C₁₀H₁₂O₂
Molecular weight	164.2 g/mol
Exact mass	164.0837
Grade	Reference Standard
HSN code	38229090
InChIKey	YYEROYLAYAVZNW-UHFFFAOYSA-N
SMILES	CC(C)(C1=CC=CC=C1)C(=O)O
PubChem CID	13222

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 2
TPSA	37.3 Å²
Synonyms	2-Phenylisobutyric Acid, alpha,alpha-DIMETHYLPHENYLACETIC ACID, benzeneacetic acid, alpha,alpha-dimethyl-, Hydratropic acid, .alpha.-methyl-, 2-phenyl-2-methylpropionic acid, alpha,alpha-dimethylbenzeneacetic acid, .alpha.,.alpha.-Dimethylphenylacetic acid, .alpha.,.alpha.-Dimethylbenzeneacetic acid, Benzeneacetic acid, .alpha.,.alpha.-dimethyl-, 2-Methyl-2-phenylpropionic acid, A,A-Dimethylbenzeneacetic acid, Dimethylphenylacetic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P337 + P317, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Methyl-2-phenylpropanoic acid?

The CAS Registry Number of 2-Methyl-2-phenylpropanoic acid is 826-55-1. It is also known as 2-Phenylisobutyric Acid, alpha,alpha-DIMETHYLPHENYLACETIC ACID, benzeneacetic acid, alpha,alpha-dimethyl-.

What is the molecular formula and molecular weight of 2-Methyl-2-phenylpropanoic acid?

2-Methyl-2-phenylpropanoic acid has the molecular formula C10H12O2 and a molecular weight of 164.2 g/mol. Its IUPAC name is 2-methyl-2-phenylpropanoic acid.

What is 2-Methyl-2-phenylpropanoic acid used for?

2-Methyl-2-phenylpropanoic acid is supplied as a characterised reference material related to Bosentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Methyl-2-phenylpropanoic acid can I order?

We supply 2-Methyl-2-phenylpropanoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Methyl-2-phenylpropanoic acid?

Yes. Every lot of 2-Methyl-2-phenylpropanoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Methyl-2-phenylpropanoic acid be shipped internationally?

Yes. 2-Methyl-2-phenylpropanoic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.