5-Amino-1-naphthol

About 5-Amino-1-naphthol

5-Amino-1-naphthol is an impurity of Duloxetine carrying the CAS registry number 83-55-6. Its molecular formula is C10H9NO and its molecular weight is 159.18 g/mol. Systematically, it is named 5-aminonaphthalen-1-ol. Alternative names: 1-Naphthalenol, 5-amino- and 1-Amino-5-naphthol.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Duloxetine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 5-Amino-1-naphthol is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Duloxetine

View every impurity, metabolite and intermediate we list for Duloxetine.

Duloxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Amino-1-naphthol
Catalogue No.	VQ-036858
CAS Number	83-55-6
IUPAC name	5-aminonaphthalen-1-ol
Molecular formula	C₁₀H₉NO
Molecular weight	159.18 g/mol
Exact mass	159.0684
Grade	Reference Standard
HSN code	38229090
InChIKey	ZBIBQNVRTVLOHQ-UHFFFAOYSA-N
SMILES	C1=CC2=C(C=CC=C2O)C(=C1)N
PubChem CID	65746

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	2 / 2
TPSA	46.3 Å²
Synonyms	1-Naphthalenol, 5-amino-, 1-Amino-5-naphthol, 1-Amino-5-hydroxynaphthalene, 5-Hydroxy-1-naphthylamine, 1-Naphthol, 5-amino-, 5-Amino-alpha-naphthol, 5-Amino-.alpha.-naphthol, 5-aminonaphthol, 5-Amino-naphthol, 5-azanylnaphthalen-1-ol, 5-amino-naphthalen-1-ol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Amino-1-naphthol?

The CAS Registry Number of 5-Amino-1-naphthol is 83-55-6. It is also known as 1-Naphthalenol, 5-amino-, 1-Amino-5-naphthol, 1-Amino-5-hydroxynaphthalene.

What is the molecular formula and molecular weight of 5-Amino-1-naphthol?

5-Amino-1-naphthol has the molecular formula C10H9NO and a molecular weight of 159.18 g/mol. Its IUPAC name is 5-aminonaphthalen-1-ol.

What is 5-Amino-1-naphthol used for?

5-Amino-1-naphthol is supplied as a characterised reference material related to Duloxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Amino-1-naphthol can I order?

We supply 5-Amino-1-naphthol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Amino-1-naphthol?

Yes. Every lot of 5-Amino-1-naphthol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Amino-1-naphthol be shipped internationally?

Yes. 5-Amino-1-naphthol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.