5-Oxo-5-(p-tolyl)pentanoic acid

Name: 5-Oxo-5-(p-tolyl)pentanoic acid
Brand: Vaqora Chemicals
SKU: VQ-040678

About 5-Oxo-5-(p-tolyl)pentanoic acid

Vaqora Chemicals supplies 5-Oxo-5-(p-tolyl)pentanoic acid, an impurity of Ezetimibe registered under CAS number 833-85-2. Its molecular formula is C12H14O3 and its molecular weight is 206.24 g/mol. Systematically, it is named 5-(4-methylphenyl)-5-oxopentanoic acid. Alternative names: p-Tolyl Keto Pentanoic Acid and 4-p-Toluoylbutyric acid.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Ezetimibe to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 5-Oxo-5-(p-tolyl)pentanoic acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ezetimibe

View every impurity, metabolite and intermediate we list for Ezetimibe.

Ezetimibe impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Oxo-5-(p-tolyl)pentanoic acid
Catalogue No.	VQ-040678
CAS Number	833-85-2
IUPAC name	5-(4-methylphenyl)-5-oxopentanoic acid
Molecular formula	C₁₂H₁₄O₃
Molecular weight	206.24 g/mol
Exact mass	206.0943
Grade	Reference Standard
HSN code	38229090
InChIKey	MCWLCBLXRSXGTF-UHFFFAOYSA-N
SMILES	CC1=CC=C(C=C1)C(=O)CCCC(=O)O
PubChem CID	70032

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	1 / 3
TPSA	54.4 Å²
Synonyms	p-Tolyl Keto Pentanoic Acid, 4-p-Toluoylbutyric acid, 4-methyl-delta-oxobenzenepentanoic acid, 5-(4-Methylphenyl)-5-oxovaleric acid, 4-p-toluoylbutyricacid, Benzenepentanoic acid,4-methyl-d-oxo-, 4-(p-Toluoyl)butyric acid, Butyric acid, 4-p-toluoyl-, 5-(4-Methylphenyl)-5-oxopentanoic acid #, Benzenepentanoic acid, 4-methyl-delta-oxo-, Benzenepentanoic acid, 4-methyl-.delta.-oxo-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Oxo-5-(p-tolyl)pentanoic acid?

The CAS Registry Number of 5-Oxo-5-(p-tolyl)pentanoic acid is 833-85-2. It is also known as p-Tolyl Keto Pentanoic Acid, 4-p-Toluoylbutyric acid, 4-methyl-delta-oxobenzenepentanoic acid.

What is the molecular formula and molecular weight of 5-Oxo-5-(p-tolyl)pentanoic acid?

5-Oxo-5-(p-tolyl)pentanoic acid has the molecular formula C12H14O3 and a molecular weight of 206.24 g/mol. Its IUPAC name is 5-(4-methylphenyl)-5-oxopentanoic acid.

What is 5-Oxo-5-(p-tolyl)pentanoic acid used for?

5-Oxo-5-(p-tolyl)pentanoic acid is supplied as a characterised reference material related to Ezetimibe. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Oxo-5-(p-tolyl)pentanoic acid can I order?

We supply 5-Oxo-5-(p-tolyl)pentanoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Oxo-5-(p-tolyl)pentanoic acid?

Yes. Every lot of 5-Oxo-5-(p-tolyl)pentanoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Oxo-5-(p-tolyl)pentanoic acid be shipped internationally?

Yes. 5-Oxo-5-(p-tolyl)pentanoic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.