Pregna-4,8-diene-3,20-dione

About Pregna-4,8-diene-3,20-dione

Pregna-4,8-diene-3,20-dione is an impurity of Progesterone carrying the CAS registry number 83603-61-6. The compound has the formula C21H28O2, corresponding to a molecular weight of 312.4 g/mol. Its systematic (IUPAC) name is (10S,13S,14R,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Progesterone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Pregna-4,8-diene-3,20-dione in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Progesterone

View every impurity, metabolite and intermediate we list for Progesterone.

Progesterone impurities

Specifications & identifiers

Chemical identifiers
Product name	Pregna-4,8-diene-3,20-dione
Catalogue No.	VQ-043681
CAS Number	83603-61-6
IUPAC name	(10S,13S,14R,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
Molecular formula	C₂₁H₂₈O₂
Molecular weight	312.4 g/mol
Exact mass	312.2089
Grade	Reference Standard
HSN code	38229090
InChIKey	OQRWANLYMLMMNO-YXYSEUPNSA-N
SMILES	CC(=O)[C@H]1CC[C@@H]2[C@@]1(CCC3=C2CCC4=CC(=O)CC[C@@]43C)C
PubChem CID	129683942

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	0 / 2
TPSA	34.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Pregna-4,8-diene-3,20-dione?

The CAS Registry Number of Pregna-4,8-diene-3,20-dione is 83603-61-6.

What is the molecular formula and molecular weight of Pregna-4,8-diene-3,20-dione?

Pregna-4,8-diene-3,20-dione has the molecular formula C21H28O2 and a molecular weight of 312.4 g/mol. Its IUPAC name is (10S,13S,14R,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one.

What is Pregna-4,8-diene-3,20-dione used for?

Pregna-4,8-diene-3,20-dione is supplied as a characterised reference material related to Progesterone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Pregna-4,8-diene-3,20-dione can I order?

We supply Pregna-4,8-diene-3,20-dione in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Pregna-4,8-diene-3,20-dione?

Yes. Every lot of Pregna-4,8-diene-3,20-dione is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Pregna-4,8-diene-3,20-dione be shipped internationally?

Yes. We export Pregna-4,8-diene-3,20-dione worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.