alpha-Arbutin

Name: alpha-Arbutin
Brand: Vaqora Chemicals
SKU: VQ-027239

About alpha-Arbutin

Vaqora Chemicals supplies alpha-Arbutin, an API impurity reference standard registered under CAS number 84380-01-8. The compound has the formula C12H16O7, corresponding to a molecular weight of 272.25 g/mol. Systematically, it is named (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol. Common synonyms include Arbutin alpha-Anomer and α-Arbutin.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

As a characterised impurity of the parent drug substance, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies alpha-Arbutin in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Specifications & identifiers

Chemical identifiers
Product name	alpha-Arbutin
Catalogue No.	VQ-027239
CAS Number	84380-01-8
IUPAC name	(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol
Molecular formula	C₁₂H₁₆O₇
Molecular weight	272.25 g/mol
Exact mass	272.0896
Grade	Reference Standard
HSN code	38229090
InChIKey	BJRNKVDFDLYUGJ-ZIQFBCGOSA-N
SMILES	C1=CC(=CC=C1O)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O
PubChem CID	158637

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.7
H-bond donors / acceptors	5 / 7
TPSA	120 Å²
Synonyms	Arbutin alpha-Anomer, α-Arbutin, P-HYDROXYPHENYL-alpha-D-GLUCOPYRANOSIDE, Derma Pella Intimate Brightening, 4-Hydroxyphenyl a-D-glucopyranoside, a-Arbutin, 4-hydroxyphenyl alpha-D-glucopyranoside, a-D-Glucopyranoside, 4-hydroxyphenyl, alpha-D-Glucopyranoside, 4-hydroxyphenyl, f inverted question mark-Arbutin, (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydro-2H-pyran-3,4,5-triol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of alpha-Arbutin?

The CAS Registry Number of alpha-Arbutin is 84380-01-8. It is also known as Arbutin alpha-Anomer, α-Arbutin, P-HYDROXYPHENYL-alpha-D-GLUCOPYRANOSIDE.

What is the molecular formula and molecular weight of alpha-Arbutin?

alpha-Arbutin has the molecular formula C12H16O7 and a molecular weight of 272.25 g/mol. Its IUPAC name is (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol.

Which grade and pack sizes of alpha-Arbutin can I order?

We supply alpha-Arbutin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with alpha-Arbutin?

Yes. Every lot of alpha-Arbutin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can alpha-Arbutin be shipped internationally?

Yes. alpha-Arbutin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.