N-Nitroso Propranolol

Name: N-Nitroso Propranolol
Brand: Vaqora Chemicals
SKU: VQ-006943

About N-Nitroso Propranolol

N-Nitroso Propranolol is a nitrosamine impurity of Propranolol carrying the CAS registry number 84418-35-9. Formula C16H20N2O3, molecular weight 288.34 g/mol. Systematically, it is named N-(2-hydroxy-3-naphthalen-1-yloxypropyl)-N-propan-2-ylnitrous amide. Alternative names: N-Nitrosopropranolol and N-nitroso-propranolol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Nitroso Propranolol in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Propranolol

View every impurity, metabolite and intermediate we list for Propranolol.

Propranolol impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso Propranolol
Catalogue No.	VQ-006943
CAS Number	84418-35-9
IUPAC name	N-(2-hydroxy-3-naphthalen-1-yloxypropyl)-N-propan-2-ylnitrous amide
Molecular formula	C₁₆H₂₀N₂O₃
Molecular weight	288.34 g/mol
Exact mass	288.1474
Grade	Reference Standard
HSN code	38229090
InChIKey	TXYRHXNLIUKPMM-UHFFFAOYSA-N
SMILES	CC(C)N(CC(COC1=CC=CC2=CC=CC=C21)O)N=O
PubChem CID	128614

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	1 / 5
TPSA	62.1 Å²
Synonyms	1-[(1-Methylethyl)nitrosoamino]-3-(1-naphthalenyloxy)-2-propanol, N-(2-hydroxy-3-(naphthalen-1-yloxy)propyl)-N-isopropylnitrous amide, N-Nitrosopropranolol, 2-Propanol, 1-((1-methylethyl)nitrosoamino)-3-(1-naphthalenyloxy)-, 2-Propanol, 1-[(1-methylethyl)nitrosoamino]-3-(1-naphthalenyloxy)-, N-nitroso-propranolol, N-Nitrosopropanolol, 1-(naphthalen-1-yloxy)-3-[nitroso(propan-2-yl)amino]propan-2-ol, N-Nitrosopropranolol (Mixture of Isomers), N-[2-hydroxy-3-(1-naphthyloxy)propyl]-N-isopropyl-nitrous amide, N-{2-Hydroxy-3-[(naphthalen-1-yl)oxy]propyl}-N-(propan-2-yl)nitrous amide

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H351Suspected of causing cancer

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso Propranolol?

The CAS Registry Number of N-Nitroso Propranolol is 84418-35-9. It is also known as 1-[(1-Methylethyl)nitrosoamino]-3-(1-naphthalenyloxy)-2-propanol, N-(2-hydroxy-3-(naphthalen-1-yloxy)propyl)-N-isopropylnitrous amide, N-Nitrosopropranolol.

What is the molecular formula and molecular weight of N-Nitroso Propranolol?

N-Nitroso Propranolol has the molecular formula C16H20N2O3 and a molecular weight of 288.34 g/mol. Its IUPAC name is N-(2-hydroxy-3-naphthalen-1-yloxypropyl)-N-propan-2-ylnitrous amide.

What is N-Nitroso Propranolol used for?

N-Nitroso Propranolol is supplied as a characterised reference material related to Propranolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso Propranolol can I order?

We supply N-Nitroso Propranolol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso Propranolol?

Yes. Every lot of N-Nitroso Propranolol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso Propranolol be shipped internationally?

Yes. N-Nitroso Propranolol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.