4-Defluoro-4-hydroxy Gefitinib

Name: 4-Defluoro-4-hydroxy Gefitinib
Brand: Vaqora Chemicals
SKU: VQ-043186

About 4-Defluoro-4-hydroxy Gefitinib

Vaqora Chemicals supplies 4-Defluoro-4-hydroxy Gefitinib, a metabolite or degradation product of Gefitinib registered under CAS number 847949-50-2. The compound has the formula C22H25ClN4O4, corresponding to a molecular weight of 444.9 g/mol. The IUPAC name is 2-chloro-4-[[7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino]phenol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Gefitinib, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 4-Defluoro-4-hydroxy Gefitinib in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Gefitinib

View every impurity, metabolite and intermediate we list for Gefitinib.

Gefitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Defluoro-4-hydroxy Gefitinib
Catalogue No.	VQ-043186
CAS Number	847949-50-2
IUPAC name	2-chloro-4-[[7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino]phenol
Molecular formula	C₂₂H₂₅ClN₄O₄
Molecular weight	444.9 g/mol
Exact mass	444.1564
Grade	Reference Standard
HSN code	38229090
InChIKey	IQWXTDMHBQBADK-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)O)Cl)OCCCN4CCOCC4
PubChem CID	11190016

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	2 / 8
TPSA	89 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Defluoro-4-hydroxy Gefitinib?

The CAS Registry Number of 4-Defluoro-4-hydroxy Gefitinib is 847949-50-2. It is also known as 2-Chloro-4-((7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl)amino)phenol, Phenol, 2-chloro-4-((7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinyl)amino)-, 2-Chloro-4-[[7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenol.

What is the molecular formula and molecular weight of 4-Defluoro-4-hydroxy Gefitinib?

4-Defluoro-4-hydroxy Gefitinib has the molecular formula C22H25ClN4O4 and a molecular weight of 444.9 g/mol. Its IUPAC name is 2-chloro-4-[[7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino]phenol.

What is 4-Defluoro-4-hydroxy Gefitinib used for?

4-Defluoro-4-hydroxy Gefitinib is supplied as a characterised reference material related to Gefitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Defluoro-4-hydroxy Gefitinib can I order?

We supply 4-Defluoro-4-hydroxy Gefitinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Defluoro-4-hydroxy Gefitinib?

Yes. Every lot of 4-Defluoro-4-hydroxy Gefitinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Defluoro-4-hydroxy Gefitinib be shipped internationally?

Yes. We export 4-Defluoro-4-hydroxy Gefitinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.