Benzo[d]thiazol-2-yl (Z)-2-(2-aminothiazol-4-… 84994-24-1

About Benzo[d]thiazol-2-yl (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetate

Benzo[d]thiazol-2-yl (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetate is an impurity of Ceftriaxone carrying the CAS registry number 84994-24-1. The compound has the formula C13H10N4O2S3, corresponding to a molecular weight of 350.4 g/mol. The IUPAC name is O-(1,3-benzothiazol-2-yl) (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoethanethioate. Common synonyms include Ceftizoxime MAEM Analog.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Ceftriaxone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Benzo[d]thiazol-2-yl (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ceftriaxone

View every impurity, metabolite and intermediate we list for Ceftriaxone.

Ceftriaxone impurities

Specifications & identifiers

Chemical identifiers
Product name	Benzo[d]thiazol-2-yl (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetate
Catalogue No.	VQ-024885
CAS Number	84994-24-1
IUPAC name	O-(1,3-benzothiazol-2-yl) (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoethanethioate
Molecular formula	C₁₃H₁₀N₄O₂S₃
Molecular weight	350.4 g/mol
Exact mass	349.9966
Grade	Reference Standard
HSN code	38229090
InChIKey	WRTVTCFELAEIEQ-YVLHZVERSA-N
SMILES	CO/N=C(/C1=CSC(=N1)N)\C(=S)OC2=NC3=CC=CC=C3S2
PubChem CID	46738096

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	1 / 9
TPSA	171 Å²
Synonyms	O-1,3-Benzothiazol-2-yl (2Z)-(2-amino-1,3-thiazol-4-yl)(methoxyimino)ethanethioate, (Z)-O-benzo[d]thiazol-2-yl 2-(2-aminothiazol-4-yl)-2-(methoxyimino)ethanethioate, Ceftizoxime MAEM Analog, (Benzothiazol-2-yl)-2-(2-Aminothiazol-4-yl)-(Z)-2-Methoxyimino Thioacetate, O-(1,3-Benzothiazol-2-yl) (2Z)-(2-amino-1,3-thiazol-4-yl)(methoxyimino)ethanethioate

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P233, P260, P271, P284, P304 + P340, P342 + P316, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Benzo[d]thiazol-2-yl (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetate?

The CAS Registry Number of Benzo[d]thiazol-2-yl (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetate is 84994-24-1. It is also known as O-1,3-Benzothiazol-2-yl (2Z)-(2-amino-1,3-thiazol-4-yl)(methoxyimino)ethanethioate, (Z)-O-benzo[d]thiazol-2-yl 2-(2-aminothiazol-4-yl)-2-(methoxyimino)ethanethioate, Ceftizoxime MAEM Analog.

What is the molecular formula and molecular weight of Benzo[d]thiazol-2-yl (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetate?

Benzo[d]thiazol-2-yl (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetate has the molecular formula C13H10N4O2S3 and a molecular weight of 350.4 g/mol. Its IUPAC name is O-(1,3-benzothiazol-2-yl) (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoethanethioate.

What is Benzo[d]thiazol-2-yl (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetate used for?

Benzo[d]thiazol-2-yl (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetate is supplied as a characterised reference material related to Ceftriaxone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Benzo[d]thiazol-2-yl (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetate can I order?

We supply Benzo[d]thiazol-2-yl (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Benzo[d]thiazol-2-yl (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetate?

Yes. Every lot of Benzo[d]thiazol-2-yl (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Benzo[d]thiazol-2-yl (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetate be shipped internationally?

Yes. Benzo[d]thiazol-2-yl (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.