2-(4-Hydroxybenzoyl)benzoic acid

About 2-(4-Hydroxybenzoyl)benzoic acid

2-(4-Hydroxybenzoyl)benzoic acid is a metabolite or degradation product of Pitofenone carrying the CAS registry number 85-57-4. Formula C14H10O4, molecular weight 242.23 g/mol. It is also known as Phthalein acid or o-(p-Hydroxybenzoyl)benzoic acid.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Pitofenone, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2-(4-Hydroxybenzoyl)benzoic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Pitofenone

View every impurity, metabolite and intermediate we list for Pitofenone.

Pitofenone impurities

Specifications & identifiers

Chemical identifiers
Product name	2-(4-Hydroxybenzoyl)benzoic acid
Catalogue No.	VQ-043367
CAS Number	85-57-4
IUPAC name	2-(4-hydroxybenzoyl)benzoic acid
Molecular formula	C₁₄H₁₀O₄
Molecular weight	242.23 g/mol
Exact mass	242.0579
Grade	Reference Standard
HSN code	38229090
InChIKey	YGTUPRIZNBMOFV-UHFFFAOYSA-N
SMILES	C1=CC=C(C(=C1)C(=O)C2=CC=C(C=C2)O)C(=O)O
PubChem CID	6814

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	2 / 4
TPSA	74.6 Å²
Synonyms	Phthalein acid, o-(p-Hydroxybenzoyl)benzoic acid, Benzoic acid, 2-(4-hydroxybenzoyl)-, Hibenzate, BENZOIC ACID, o-(p-HYDROXYBENZOYL)-, Hybenzoate, 2-[(4-hydroxyphenyl)carbonyl]benzoic acid, Benzoic acid, p-(p-hydroxybenzoyl)-, 2-(p-Hydroxybenzoyl)benzoic acid, 2-(4-hydroxybenzoyl)benzoic acid, AldrichCPR

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P305 + P351 + P338, P330, P337 + P317, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-(4-Hydroxybenzoyl)benzoic acid?

The CAS Registry Number of 2-(4-Hydroxybenzoyl)benzoic acid is 85-57-4. It is also known as Phthalein acid, o-(p-Hydroxybenzoyl)benzoic acid, Benzoic acid, 2-(4-hydroxybenzoyl)-.

What is the molecular formula and molecular weight of 2-(4-Hydroxybenzoyl)benzoic acid?

2-(4-Hydroxybenzoyl)benzoic acid has the molecular formula C14H10O4 and a molecular weight of 242.23 g/mol. Its IUPAC name is 2-(4-hydroxybenzoyl)benzoic acid.

What is 2-(4-Hydroxybenzoyl)benzoic acid used for?

2-(4-Hydroxybenzoyl)benzoic acid is supplied as a characterised reference material related to Pitofenone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-(4-Hydroxybenzoyl)benzoic acid can I order?

We supply 2-(4-Hydroxybenzoyl)benzoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-(4-Hydroxybenzoyl)benzoic acid?

Yes. Every lot of 2-(4-Hydroxybenzoyl)benzoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-(4-Hydroxybenzoyl)benzoic acid be shipped internationally?

Yes. 2-(4-Hydroxybenzoyl)benzoic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.