Methyl a-Bromo-2-chlorophenylacetate

Name: Methyl a-Bromo-2-chlorophenylacetate
Brand: Vaqora Chemicals
SKU: VQ-043470

About Methyl a-Bromo-2-chlorophenylacetate

Methyl a-Bromo-2-chlorophenylacetate (CAS 85259-19-4) is a process intermediate or related compound of Clopidogrel offered by Vaqora Chemicals. Its molecular formula is C9H8BrClO2 and its molecular weight is 263.51 g/mol. Systematically, it is named methyl 2-bromo-2-(2-chlorophenyl)acetate. Alternative names: Methyl alpha-bromo-2-chlorophenylacetate and methyl bromo(2-chlorophenyl)acetate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Clopidogrel, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Clopidogrel

View every impurity, metabolite and intermediate we list for Clopidogrel.

Clopidogrel impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl a-Bromo-2-chlorophenylacetate
Catalogue No.	VQ-043470
CAS Number	85259-19-4
IUPAC name	methyl 2-bromo-2-(2-chlorophenyl)acetate
Molecular formula	C₉H₈BrClO₂
Molecular weight	263.51 g/mol
Exact mass	261.9396
InChIKey	HMBUCZUZRQQJQD-UHFFFAOYSA-N
SMILES	COC(=O)C(C1=CC=CC=C1Cl)Br
PubChem CID	10730282

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	0 / 2
TPSA	26.3 Å²
Synonyms	Methyl alpha-bromo-2-chlorophenylacetate, Benzeneacetic acid, alpha-bromo-2-chloro-, methyl ester, methyl bromo(2-chlorophenyl)acetate, alpha-Bromo-2-chlorophenylacetic Acid Methyl Ester, Methyl alpha-bromo-2-chloro-phenylacetate, 2-Bromo-2-(2-chlorophenyl)acetic acid methyl ester, Methyl, _-Bromo-2-chlorophenylacetate, Methyl 2-bromo-2'-chlorophenylacetate, methyl alpha-bromo-o-chlorophenylacetate, 2-chloro-alpha-methoxycarbonylbenzyl bromide

Safety & hazard information (GHS)

Corrosive

Signal word: Danger

Hazard statements

H290May be corrosive to metals
H314Causes severe skin burns and eye damage
H318Causes serious eye damage

Precautionary statements: P234, P260, P264, P264 + P265, P280, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P317, P321, P363, P390, P405, P406, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl a-Bromo-2-chlorophenylacetate?

The CAS Registry Number of Methyl a-Bromo-2-chlorophenylacetate is 85259-19-4. It is also known as Methyl alpha-bromo-2-chlorophenylacetate, Benzeneacetic acid, alpha-bromo-2-chloro-, methyl ester, methyl bromo(2-chlorophenyl)acetate.

What is the molecular formula and molecular weight of Methyl a-Bromo-2-chlorophenylacetate?

Methyl a-Bromo-2-chlorophenylacetate has the molecular formula C9H8BrClO2 and a molecular weight of 263.51 g/mol. Its IUPAC name is methyl 2-bromo-2-(2-chlorophenyl)acetate.

What is Methyl a-Bromo-2-chlorophenylacetate used for?

Methyl a-Bromo-2-chlorophenylacetate is supplied as a characterised reference material related to Clopidogrel. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl a-Bromo-2-chlorophenylacetate can I order?

We supply Methyl a-Bromo-2-chlorophenylacetate, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl a-Bromo-2-chlorophenylacetate?

Yes. Every lot of Methyl a-Bromo-2-chlorophenylacetate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl a-Bromo-2-chlorophenylacetate be shipped internationally?

Yes. Methyl a-Bromo-2-chlorophenylacetate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.