Rosuvastatin (6R)-Lactone Impurity

About Rosuvastatin (6R)-Lactone Impurity

Rosuvastatin (6R)-Lactone Impurity is an impurity of Rosuvastatin carrying the CAS registry number 854898-46-7. Its molecular formula is C22H26FN3O5S and its molecular weight is 463.5 g/mol. Alternative names: Rosuvastatin Impurity 58.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Rosuvastatin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Rosuvastatin (6R)-Lactone Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Rosuvastatin

View every impurity, metabolite and intermediate we list for Rosuvastatin.

Rosuvastatin impurities

Specifications & identifiers

Chemical identifiers
Product name	Rosuvastatin (6R)-Lactone Impurity
Catalogue No.	VQ-045425
CAS Number	854898-46-7
IUPAC name	N-[(6R)-8-fluoro-6-[(2S,4R)-4-hydroxy-6-oxooxan-2-yl]-4-propan-2-yl-5,6-dihydrobenzo[h]quinazolin-2-yl]-N-methylmethanesulfonamide
Molecular formula	C₂₂H₂₆FN₃O₅S
Molecular weight	463.5 g/mol
Exact mass	463.1577
Grade	Reference Standard
HSN code	38229090
InChIKey	VLAHUUGOOLLUEH-QBIMZIAESA-N
SMILES	CC(C)C1=NC(=NC2=C1C[C@H](C3=C2C=CC(=C3)F)[C@@H]4C[C@H](CC(=O)O4)O)N(C)S(=O)(=O)C
PubChem CID	131667983

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	1 / 9
TPSA	118 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rosuvastatin (6R)-Lactone Impurity?

The CAS Registry Number of Rosuvastatin (6R)-Lactone Impurity is 854898-46-7. It is also known as Rosuvastatin Impurity 58.

What is the molecular formula and molecular weight of Rosuvastatin (6R)-Lactone Impurity?

Rosuvastatin (6R)-Lactone Impurity has the molecular formula C22H26FN3O5S and a molecular weight of 463.5 g/mol. Its IUPAC name is N-[(6R)-8-fluoro-6-[(2S,4R)-4-hydroxy-6-oxooxan-2-yl]-4-propan-2-yl-5,6-dihydrobenzo[h]quinazolin-2-yl]-N-methylmethanesulfonamide.

What is Rosuvastatin (6R)-Lactone Impurity used for?

Rosuvastatin (6R)-Lactone Impurity is supplied as a characterised reference material related to Rosuvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rosuvastatin (6R)-Lactone Impurity can I order?

We supply Rosuvastatin (6R)-Lactone Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rosuvastatin (6R)-Lactone Impurity?

Yes. Every lot of Rosuvastatin (6R)-Lactone Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rosuvastatin (6R)-Lactone Impurity be shipped internationally?

Yes. We export Rosuvastatin (6R)-Lactone Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.