N-Desmethyl Azithromycin B

About N-Desmethyl Azithromycin B

N-Desmethyl Azithromycin B is a metabolite or degradation product of Azithromycin carrying the CAS registry number 857078-26-3. The compound has the formula C37H70N2O11, corresponding to a molecular weight of 719.0 g/mol. Common synonyms include Azithromycin 3-Deoxy N-Desmethyl.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Azithromycin, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Desmethyl Azithromycin B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Azithromycin

View every impurity, metabolite and intermediate we list for Azithromycin.

Azithromycin impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl Azithromycin B
Catalogue No.	VQ-029337
CAS Number	857078-26-3
IUPAC name	(2R,3R,4S,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-4,10-dihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one
Molecular formula	C₃₇H₇₀N₂O₁₁
Molecular weight	719 g/mol
Exact mass	718.498
Grade	Reference Standard
HSN code	38229090
InChIKey	VUPHMOHDOYHVSB-VZIFPMBTSA-N
SMILES	CC[C@@H]1[C@@H]([C@@H]([C@H](NC[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)C
PubChem CID	171370600

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	5 / 13
TPSA	169 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl Azithromycin B?

The CAS Registry Number of N-Desmethyl Azithromycin B is 857078-26-3. It is also known as Azithromycin 3-Deoxy N-Desmethyl.

What is the molecular formula and molecular weight of N-Desmethyl Azithromycin B?

N-Desmethyl Azithromycin B has the molecular formula C37H70N2O11 and a molecular weight of 719 g/mol.

What is N-Desmethyl Azithromycin B used for?

N-Desmethyl Azithromycin B is supplied as a characterised reference material related to Azithromycin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl Azithromycin B can I order?

We supply N-Desmethyl Azithromycin B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl Azithromycin B?

Yes. Every lot of N-Desmethyl Azithromycin B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl Azithromycin B be shipped internationally?

Yes. We export N-Desmethyl Azithromycin B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.