2-(Chloromethyl)benzoic Acid

About 2-(Chloromethyl)benzoic Acid

2-(Chloromethyl)benzoic Acid is a process intermediate or related compound of Imatinib carrying the CAS registry number 85888-81-9. With the molecular formula C8H7ClO2, it has a molar mass of 170.59 g/mol. Common synonyms include alpha-chloro-toluic acid and (chloromethyl)benzoic acid.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 2 hazard statements. Review the Safety Data Sheet before use.

Process chemists and analysts use it when developing synthetic routes to Imatinib, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Imatinib

View every impurity, metabolite and intermediate we list for Imatinib.

Imatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	2-(Chloromethyl)benzoic Acid
Catalogue No.	VQ-048651
CAS Number	85888-81-9
IUPAC name	2-(chloromethyl)benzoic acid
Molecular formula	C₈H₇ClO₂
Molecular weight	170.59 g/mol
Exact mass	170.0135
InChIKey	YTEUDCIEJDRJTM-UHFFFAOYSA-N
SMILES	C1=CC=C(C(=C1)CCl)C(=O)O
PubChem CID	296106

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	1 / 2
TPSA	37.3 Å²

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H314Causes severe skin burns and eye damage

Precautionary statements: P260, P264, P270, P280, P301 + P317, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P321, P330, P363, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-(Chloromethyl)benzoic Acid?

The CAS Registry Number of 2-(Chloromethyl)benzoic Acid is 85888-81-9. It is also known as alpha-chloro-toluic acid, (chloromethyl)benzoic acid, alpha-Chloro-o-toluic acid.

What is the molecular formula and molecular weight of 2-(Chloromethyl)benzoic Acid?

2-(Chloromethyl)benzoic Acid has the molecular formula C8H7ClO2 and a molecular weight of 170.59 g/mol. Its IUPAC name is 2-(chloromethyl)benzoic acid.

What is 2-(Chloromethyl)benzoic Acid used for?

2-(Chloromethyl)benzoic Acid is supplied as a characterised reference material related to Imatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-(Chloromethyl)benzoic Acid can I order?

We supply 2-(Chloromethyl)benzoic Acid, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-(Chloromethyl)benzoic Acid?

Yes. Every lot of 2-(Chloromethyl)benzoic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-(Chloromethyl)benzoic Acid be shipped internationally?

Yes. 2-(Chloromethyl)benzoic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.