Latanoprostene Bunod

About Latanoprostene Bunod

Latanoprostene Bunod is an impurity of Latanoprost carrying the CAS registry number 860005-21-6. Formula C27H41NO8, molecular weight 507.6 g/mol. Its systematic (IUPAC) name is 4-nitrooxybutyl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate. Alternative names: NCX-116 and latanoprosteno bunod.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Latanoprost to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Latanoprostene Bunod is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Latanoprost

View every impurity, metabolite and intermediate we list for Latanoprost.

Latanoprost impurities

Specifications & identifiers

Chemical identifiers
Product name	Latanoprostene Bunod
Catalogue No.	VQ-026383
CAS Number	860005-21-6
IUPAC name	4-nitrooxybutyl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate
Molecular formula	C₂₇H₄₁NO₈
Molecular weight	507.6 g/mol
Exact mass	507.2832
Grade	Reference Standard
HSN code	38229090
InChIKey	LOVMMUBRQUFEAH-UIEAZXIASA-N
SMILES	C1[C@H]([C@@H]([C@H]([C@H]1O)C/C=C\CCCC(=O)OCCCCO[N+](=O)[O-])CC[C@H](CCC2=CC=CC=C2)O)O
PubChem CID	11156438

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	3 / 8
TPSA	142 Å²

Safety & hazard information (GHS)

Flammable

Health hazard

Signal word: Danger

Hazard statements

H242Heating may cause a fire
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P210, P234, P235, P240, P280, P318, P370 + P378, P403, P405, P410, P411, P420, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Latanoprostene Bunod?

The CAS Registry Number of Latanoprostene Bunod is 860005-21-6. It is also known as NCX-116, latanoprosteno bunod, latanoprostenum bunodum.

What is the molecular formula and molecular weight of Latanoprostene Bunod?

Latanoprostene Bunod has the molecular formula C27H41NO8 and a molecular weight of 507.6 g/mol. Its IUPAC name is 4-nitrooxybutyl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate.

What is Latanoprostene Bunod used for?

Latanoprostene Bunod is supplied as a characterised reference material related to Latanoprost. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Latanoprostene Bunod can I order?

We supply Latanoprostene Bunod in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Latanoprostene Bunod?

Yes. Every lot of Latanoprostene Bunod is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Latanoprostene Bunod be shipped internationally?

Yes. Latanoprostene Bunod is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.