4-Hydroxysolifenacin

About 4-Hydroxysolifenacin

4-Hydroxysolifenacin is a metabolite or degradation product of Solifenacin carrying the CAS registry number 861998-77-8. Its molecular formula is C23H26N2O3 and its molecular weight is 378.5 g/mol. Its systematic (IUPAC) name is [(3R)-1-azabicyclo[2.2.2]octan-3-yl] (1S,4R)-4-hydroxy-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate. It is also known as Solifenacin (m3) or 4-Hydroxy solifenacin, (4R)-.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Solifenacin, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 4-Hydroxysolifenacin in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Solifenacin

View every impurity, metabolite and intermediate we list for Solifenacin.

Solifenacin impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxysolifenacin
Catalogue No.	VQ-033915
CAS Number	861998-77-8
IUPAC name	[(3R)-1-azabicyclo[2.2.2]octan-3-yl] (1S,4R)-4-hydroxy-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate
Molecular formula	C₂₃H₂₆N₂O₃
Molecular weight	378.5 g/mol
Exact mass	378.1943
Grade	Reference Standard
HSN code	38229090
InChIKey	LRNNBJBAUXSVMH-FKBYEOEOSA-N
SMILES	C1CN2CCC1[C@H](C2)OC(=O)N3C[C@@H](C4=CC=CC=C4[C@@H]3C5=CC=CC=C5)O
PubChem CID	71749342

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	1 / 4
TPSA	53 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxysolifenacin?

The CAS Registry Number of 4-Hydroxysolifenacin is 861998-77-8. It is also known as Solifenacin (m3), 4-Hydroxy solifenacin, (4R)-, (4R)-4-hydroxy solifenacin.

What is the molecular formula and molecular weight of 4-Hydroxysolifenacin?

4-Hydroxysolifenacin has the molecular formula C23H26N2O3 and a molecular weight of 378.5 g/mol. Its IUPAC name is [(3R)-1-azabicyclo[2.2.2]octan-3-yl] (1S,4R)-4-hydroxy-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate.

What is 4-Hydroxysolifenacin used for?

4-Hydroxysolifenacin is supplied as a characterised reference material related to Solifenacin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxysolifenacin can I order?

We supply 4-Hydroxysolifenacin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxysolifenacin?

Yes. Every lot of 4-Hydroxysolifenacin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxysolifenacin be shipped internationally?

Yes. We export 4-Hydroxysolifenacin worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.