2,4-Dichloro-5-fluorobenzoyl chloride

About 2,4-Dichloro-5-fluorobenzoyl chloride

2,4-Dichloro-5-fluorobenzoyl chloride is an impurity of Lamotrigine carrying the CAS registry number 86393-34-2. Its molecular formula is C7H2Cl3FO and its molecular weight is 227.4 g/mol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Lamotrigine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 2,4-Dichloro-5-fluorobenzoyl chloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Lamotrigine

View every impurity, metabolite and intermediate we list for Lamotrigine.

Lamotrigine impurities

Specifications & identifiers

Chemical identifiers
Product name	2,4-Dichloro-5-fluorobenzoyl chloride
Catalogue No.	VQ-036337
CAS Number	86393-34-2
IUPAC name	2,4-dichloro-5-fluorobenzoyl chloride
Molecular formula	C₇H₂Cl₃FO
Molecular weight	227.4 g/mol
Exact mass	225.9155
Grade	Reference Standard
HSN code	38229090
InChIKey	RPZXUSJCSDQNTE-UHFFFAOYSA-N
SMILES	C1=C(C(=CC(=C1F)Cl)Cl)C(=O)Cl
PubChem CID	2736821

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	0 / 2
TPSA	17.1 Å²

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H335May cause respiratory irritation
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P261, P264, P264 + P265, P271, P272, P273, P280, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P332 + P317, P333 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,4-Dichloro-5-fluorobenzoyl chloride?

The CAS Registry Number of 2,4-Dichloro-5-fluorobenzoyl chloride is 86393-34-2.

What is the molecular formula and molecular weight of 2,4-Dichloro-5-fluorobenzoyl chloride?

2,4-Dichloro-5-fluorobenzoyl chloride has the molecular formula C7H2Cl3FO and a molecular weight of 227.4 g/mol. Its IUPAC name is 2,4-dichloro-5-fluorobenzoyl chloride.

What is 2,4-Dichloro-5-fluorobenzoyl chloride used for?

2,4-Dichloro-5-fluorobenzoyl chloride is supplied as a characterised reference material related to Lamotrigine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,4-Dichloro-5-fluorobenzoyl chloride can I order?

We supply 2,4-Dichloro-5-fluorobenzoyl chloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,4-Dichloro-5-fluorobenzoyl chloride?

Yes. Every lot of 2,4-Dichloro-5-fluorobenzoyl chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,4-Dichloro-5-fluorobenzoyl chloride be shipped internationally?

Yes. 2,4-Dichloro-5-fluorobenzoyl chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.