Empagliflozin Destetrahydrofuran Impurity

About Empagliflozin Destetrahydrofuran Impurity

Empagliflozin Destetrahydrofuran Impurity is an impurity of Empagliflozin carrying the CAS registry number 864070-37-1, specified at 99% purity. With the molecular formula C19H21ClO6, it has a molar mass of 380.8 g/mol. Its systematic (IUPAC) name is (2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-hydroxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol. It is also known as Empagliflozin EPG-8 Impurity or O-Desethyl Dapagliflozin.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Empagliflozin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Empagliflozin Destetrahydrofuran Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Empagliflozin

View every impurity, metabolite and intermediate we list for Empagliflozin.

Empagliflozin impurities

Specifications & identifiers

Chemical identifiers
Product name	Empagliflozin Destetrahydrofuran Impurity
Catalogue No.	VQ-004862
CAS Number	864070-37-1
IUPAC name	(2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-hydroxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
Molecular formula	C₁₉H₂₁ClO₆
Molecular weight	380.8 g/mol
Exact mass	380.1027
Grade	Reference Standard
Purity / assay	99%
HSN code	38229090
InChIKey	ODQAIMBPQWETBE-FQBWVUSXSA-N
SMILES	C1=CC(=CC=C1CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)Cl)O
PubChem CID	44580555

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	5 / 6
TPSA	110 Å²
Synonyms	Empagliflozin EPG-8 Impurity, (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-hydroxyphenyl)methyl]phenyl]-D-glucitol, O-Desethyl Dapagliflozin, Empagliflozin Impurity 5, Dapagliflozin metabolite M8, D-Glucitol, 1,5-anhydro-1-C-(4-chloro-3-((4-hydroxyphenyl)methyl)phenyl)-, (1S)-, D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-hydroxyphenyl)methyl]phenyl]-, (1S)-, Dapagliflozin Impurity 13, Dapagliflozin Impurity L, O-Desethyl Dapagliflozin (>80%), Empagliflozin-4, Jardiance Impurity H

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P264, P264 + P265, P270, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Empagliflozin Destetrahydrofuran Impurity?

The CAS Registry Number of Empagliflozin Destetrahydrofuran Impurity is 864070-37-1. It is also known as Empagliflozin EPG-8 Impurity, (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-hydroxyphenyl)methyl]phenyl]-D-glucitol, O-Desethyl Dapagliflozin.

What is the molecular formula and molecular weight of Empagliflozin Destetrahydrofuran Impurity?

Empagliflozin Destetrahydrofuran Impurity has the molecular formula C19H21ClO6 and a molecular weight of 380.8 g/mol. Its IUPAC name is (2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-hydroxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol.

What is Empagliflozin Destetrahydrofuran Impurity used for?

Empagliflozin Destetrahydrofuran Impurity is supplied as a characterised reference material related to Empagliflozin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Empagliflozin Destetrahydrofuran Impurity can I order?

We supply Empagliflozin Destetrahydrofuran Impurity in Reference Standard (99%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Empagliflozin Destetrahydrofuran Impurity?

Yes. Every lot of Empagliflozin Destetrahydrofuran Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Empagliflozin Destetrahydrofuran Impurity be shipped internationally?

Yes. Empagliflozin Destetrahydrofuran Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.