Ethyl (S)-4-chloro-3-hydroxybutyrate

Name: Ethyl (S)-4-chloro-3-hydroxybutyrate
Brand: Vaqora Chemicals
SKU: VQ-029254

About Ethyl (S)-4-chloro-3-hydroxybutyrate

Vaqora Chemicals supplies Ethyl (S)-4-chloro-3-hydroxybutyrate, a metabolite or degradation product of Rosuvastatin registered under CAS number 86728-85-0. With the molecular formula C6H11ClO3, it has a molar mass of 166.6 g/mol. Its systematic (IUPAC) name is ethyl (3S)-4-chloro-3-hydroxybutanoate. Common synonyms include ethyl (S)-4-chloro-3-hydroxybutanoate and ethyl (S)-(-)-4-chloro-3-hydroxybutanoate.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Rosuvastatin, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Rosuvastatin

View every impurity, metabolite and intermediate we list for Rosuvastatin.

Rosuvastatin impurities

Specifications & identifiers

Chemical identifiers
Product name	Ethyl (S)-4-chloro-3-hydroxybutyrate
Catalogue No.	VQ-029254
CAS Number	86728-85-0
IUPAC name	ethyl (3S)-4-chloro-3-hydroxybutanoate
Molecular formula	C₆H₁₁ClO₃
Molecular weight	166.6 g/mol
Exact mass	166.0397
Grade	Reference Standard
HSN code	38229090
InChIKey	ZAJNMXDBJKCCAT-YFKPBYRVSA-N
SMILES	CCOC(=O)C[C@@H](CCl)O
PubChem CID	7019277

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	1 / 3
TPSA	46.5 Å²
Synonyms	ethyl (S)-4-chloro-3-hydroxybutanoate, (S)-4-Chloro-3-hydroxybutyric Acid Ethyl Ester, ethyl (S)-(-)-4-chloro-3-hydroxybutanoate, (S)-Ethyl 4-chloro-3-hydroxybutanoate, ethyl (3S)-4-chloro-3-hydroxy-butanoate, (S)-4-Chloro-3-hydroxy-n-butyric Acid Ethyl Ester, (3s)-4-chloro-3-hydroxybutyric acid ethyl ester, (S)-ethyl-4-chloro-3-hydroxybutyrate

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P302 + P352, P305 + P354 + P338, P317, P321, P330, P332 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethyl (S)-4-chloro-3-hydroxybutyrate?

The CAS Registry Number of Ethyl (S)-4-chloro-3-hydroxybutyrate is 86728-85-0. It is also known as ethyl (S)-4-chloro-3-hydroxybutanoate, (S)-4-Chloro-3-hydroxybutyric Acid Ethyl Ester, ethyl (S)-(-)-4-chloro-3-hydroxybutanoate.

What is the molecular formula and molecular weight of Ethyl (S)-4-chloro-3-hydroxybutyrate?

Ethyl (S)-4-chloro-3-hydroxybutyrate has the molecular formula C6H11ClO3 and a molecular weight of 166.6 g/mol. Its IUPAC name is ethyl (3S)-4-chloro-3-hydroxybutanoate.

What is Ethyl (S)-4-chloro-3-hydroxybutyrate used for?

Ethyl (S)-4-chloro-3-hydroxybutyrate is supplied as a characterised reference material related to Rosuvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethyl (S)-4-chloro-3-hydroxybutyrate can I order?

We supply Ethyl (S)-4-chloro-3-hydroxybutyrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethyl (S)-4-chloro-3-hydroxybutyrate?

Yes. Every lot of Ethyl (S)-4-chloro-3-hydroxybutyrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethyl (S)-4-chloro-3-hydroxybutyrate be shipped internationally?

Yes. Ethyl (S)-4-chloro-3-hydroxybutyrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.