4-Amino-2,6-dihydroxypyrimidine

About 4-Amino-2,6-dihydroxypyrimidine

4-Amino-2,6-dihydroxypyrimidine is a process intermediate or related compound of Tegoprazan carrying the CAS registry number 873-83-6. The compound has the formula C4H5N3O2, corresponding to a molecular weight of 127.1 g/mol. The IUPAC name is 6-amino-1H-pyrimidine-2,4-dione. It is also known as 6-Aminouracil or 2,4(1H,3H)-Pyrimidinedione, 6-amino-.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Tegoprazan, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Tegoprazan

View every impurity, metabolite and intermediate we list for Tegoprazan.

Tegoprazan impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Amino-2,6-dihydroxypyrimidine
Catalogue No.	VQ-040252
CAS Number	873-83-6
IUPAC name	6-amino-1H-pyrimidine-2,4-dione
Molecular formula	C₄H₅N₃O₂
Molecular weight	127.1 g/mol
Exact mass	127.0382
HSN code	2933
InChIKey	LNDZXOWGUAIUBG-UHFFFAOYSA-N
SMILES	C1=C(NC(=O)NC1=O)N
PubChem CID	70120

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.6
H-bond donors / acceptors	3 / 3
TPSA	84.2 Å²
Synonyms	6-Aminouracil, 2,4(1H,3H)-Pyrimidinedione, 6-amino-, 6-aminopyrimidine-2,4(1H,3H)-dione, 6-aminopyrimidine-2,4-diol, 6-Amino-2,4-pyrimidinediol, 6-Amino-2,4-dihydroxypyrimidine, Cytosine, 6-hydroxy-, Uracil, 6-amino-, 4-Amino-2,6-pyrimidinediol, 4-Amino-2,6-dioxypyrimidine, 4-Amino-2,6-dihydroxylpyrimidine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Amino-2,6-dihydroxypyrimidine?

The CAS Registry Number of 4-Amino-2,6-dihydroxypyrimidine is 873-83-6. It is also known as 6-Aminouracil, 2,4(1H,3H)-Pyrimidinedione, 6-amino-, 6-aminopyrimidine-2,4(1H,3H)-dione.

What is the molecular formula and molecular weight of 4-Amino-2,6-dihydroxypyrimidine?

4-Amino-2,6-dihydroxypyrimidine has the molecular formula C4H5N3O2 and a molecular weight of 127.1 g/mol. Its IUPAC name is 6-amino-1H-pyrimidine-2,4-dione.

What is 4-Amino-2,6-dihydroxypyrimidine used for?

4-Amino-2,6-dihydroxypyrimidine is supplied as a characterised reference material related to Tegoprazan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Amino-2,6-dihydroxypyrimidine can I order?

We supply 4-Amino-2,6-dihydroxypyrimidine, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Amino-2,6-dihydroxypyrimidine?

Yes. Every lot of 4-Amino-2,6-dihydroxypyrimidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Amino-2,6-dihydroxypyrimidine be shipped internationally?

Yes. 4-Amino-2,6-dihydroxypyrimidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.