[Chloro(phosphono)methyl]phosphonic acid

About [Chloro(phosphono)methyl]phosphonic acid

[Chloro(phosphono)methyl]phosphonic acid is an impurity of Clodronate carrying the CAS registry number 87591-00-2. With the molecular formula CH5ClO6P2, it has a molar mass of 210.45 g/mol. Common synonyms include (chloromethylene)bis(phosphonic acid) and Phosphonic acid, (chloromethylene)bis-.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This Clodronate impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, [Chloro(phosphono)methyl]phosphonic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Clodronate

View every impurity, metabolite and intermediate we list for Clodronate.

Clodronate impurities

Specifications & identifiers

Chemical identifiers
Product name	[Chloro(phosphono)methyl]phosphonic acid
Catalogue No.	VQ-027260
CAS Number	87591-00-2
IUPAC name	[chloro(phosphono)methyl]phosphonic acid
Molecular formula	CH₅ClO₆P₂
Molecular weight	210.45 g/mol
Exact mass	209.925
Grade	Reference Standard
HSN code	38229090
InChIKey	FVXIZAQSPMLAMD-UHFFFAOYSA-N
SMILES	C(P(=O)(O)O)(P(=O)(O)O)Cl
PubChem CID	462036

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.6
H-bond donors / acceptors	4 / 6
TPSA	115 Å²
Synonyms	(chloromethylene)bis(phosphonic acid), Phosphonic acid, (chloromethylene)bis-, (Chloromethylene)bisphosphonic acid, chloromethane diphosphonate, (Chloromethanediyl)bis(phosphonic acid), P,P'-(Chloromethylene)bis[phosphonic acid], Phosphonic acid, P,P'-(chloromethylene)bis-

Safety & hazard information (GHS)

Corrosive

Signal word: Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements: P260, P264, P280, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P321, P363, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of [Chloro(phosphono)methyl]phosphonic acid?

The CAS Registry Number of [Chloro(phosphono)methyl]phosphonic acid is 87591-00-2. It is also known as (chloromethylene)bis(phosphonic acid), Phosphonic acid, (chloromethylene)bis-, (Chloromethylene)bisphosphonic acid.

What is the molecular formula and molecular weight of [Chloro(phosphono)methyl]phosphonic acid?

[Chloro(phosphono)methyl]phosphonic acid has the molecular formula CH5ClO6P2 and a molecular weight of 210.45 g/mol. Its IUPAC name is [chloro(phosphono)methyl]phosphonic acid.

What is [Chloro(phosphono)methyl]phosphonic acid used for?

[Chloro(phosphono)methyl]phosphonic acid is supplied as a characterised reference material related to Clodronate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of [Chloro(phosphono)methyl]phosphonic acid can I order?

We supply [Chloro(phosphono)methyl]phosphonic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with [Chloro(phosphono)methyl]phosphonic acid?

Yes. Every lot of [Chloro(phosphono)methyl]phosphonic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can [Chloro(phosphono)methyl]phosphonic acid be shipped internationally?

Yes. [Chloro(phosphono)methyl]phosphonic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.