Nitrosoantipyrine

Name: Nitrosoantipyrine
Brand: Vaqora Chemicals
SKU: VQ-023085

About Nitrosoantipyrine

Nitrosoantipyrine (CAS 885-11-0) is a stable isotope labelled analogue related to Antipyrine offered by Vaqora Chemicals. Its molecular formula is C11H11N3O2 and its molecular weight is 217.22 g/mol. Systematically, it is named 1,5-dimethyl-4-nitroso-2-phenylpyrazol-3-one. It is also known as N-Nitrosoantipyrine or 4-Nitrosoantipyrine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Antipyrine and related analytes in bioanalytical, pharmacokinetic and impurity studies. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Nitrosoantipyrine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Antipyrine

View every impurity, metabolite and intermediate we list for Antipyrine.

Antipyrine impurities

Specifications & identifiers

Chemical identifiers
Product name	Nitrosoantipyrine
Catalogue No.	VQ-023085
CAS Number	885-11-0
IUPAC name	1,5-dimethyl-4-nitroso-2-phenylpyrazol-3-one
Molecular formula	C₁₁H₁₁N₃O₂
Molecular weight	217.22 g/mol
Exact mass	217.0851
Grade	Reference Standard
HSN code	38229090
InChIKey	IEODZSWSXNQPQL-UHFFFAOYSA-N
SMILES	CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N=O
PubChem CID	13443

Physical properties
Physical form	Solid
LogP (XLogP3)	0.2
H-bond donors / acceptors	0 / 4
TPSA	53 Å²
Synonyms	N-Nitrosoantipyrine, 4-Nitrosoantipyrine, 4-Nitrosoantipyrin, 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-nitroso-2-phenyl-, 1,2-Dihydro-1,5-dimethyl-4-nitroso-2-phenyl-3H-pyrazol-3-one, 1,5-Dimethyl-4-nitroso-2-phenyl-1,2-dihydro-3H-pyrazol-3-one, 3H-Pyrazol-3-one,1,2-dihydro-1,5-dimethyl-4-nitroso-2-phenyl-, 1,5-dimethyl-4-nitroso-2-phenyl-pyrazol-3-one, 2,3-Dimethyl-4-nitroso-1-phenyl-3-pyrazolin-5-one, 1,5-dimethyl-4-nitroso-2-phenyl-1H-pyrazol-3(2H)-one, Nitrosoantipyrin

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nitrosoantipyrine?

The CAS Registry Number of Nitrosoantipyrine is 885-11-0. It is also known as N-Nitrosoantipyrine, 4-Nitrosoantipyrine, 4-Nitrosoantipyrin.

What is the molecular formula and molecular weight of Nitrosoantipyrine?

Nitrosoantipyrine has the molecular formula C11H11N3O2 and a molecular weight of 217.22 g/mol. Its IUPAC name is 1,5-dimethyl-4-nitroso-2-phenylpyrazol-3-one.

What is Nitrosoantipyrine used for?

Nitrosoantipyrine is supplied as a characterised reference material related to Antipyrine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nitrosoantipyrine can I order?

We supply Nitrosoantipyrine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nitrosoantipyrine?

Yes. Every lot of Nitrosoantipyrine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nitrosoantipyrine be shipped internationally?

Yes. Nitrosoantipyrine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.