D -Glucoheptono-1,4-lactone

About D -Glucoheptono-1,4-lactone

D -Glucoheptono-1,4-lactone is an impurity of Canagliflozin carrying the CAS registry number 89-67-8. With the molecular formula C7H12O7, it has a molar mass of 208.17 g/mol. The IUPAC name is (3R,4S,5S)-3,4-dihydroxy-5-[(1R,2R)-1,2,3-trihydroxypropyl]oxolan-2-one. It is also known as Heptono-1,4-lactone or D-glycero-D-gulo-Heptonic acid, gamma-lactone.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Canagliflozin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer D -Glucoheptono-1,4-lactone in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Canagliflozin

View every impurity, metabolite and intermediate we list for Canagliflozin.

Canagliflozin impurities

Specifications & identifiers

Chemical identifiers
Product name	D -Glucoheptono-1,4-lactone
Catalogue No.	VQ-036110
CAS Number	89-67-8
IUPAC name	(3R,4S,5S)-3,4-dihydroxy-5-[(1R,2R)-1,2,3-trihydroxypropyl]oxolan-2-one
Molecular formula	C₇H₁₂O₇
Molecular weight	208.17 g/mol
Exact mass	208.0583
Grade	Reference Standard
HSN code	38229090
InChIKey	VIVCRCODGMFTFY-DVKNGEFBSA-N
SMILES	C([C@H]([C@H]([C@H]1[C@H]([C@H](C(=O)O1)O)O)O)O)O
PubChem CID	2723843

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.6
H-bond donors / acceptors	5 / 7
TPSA	127 Å²
Synonyms	Heptono-1,4-lactone, D-glycero-D-gulo-Heptonic acid, gamma-lactone, (3R,4S,5S)-3,4-dihydroxy-5-((1R,2R)-1,2,3-trihydroxypropyl)dihydrofuran-2(3H)-one, 1,4-heptonolactone, (3R,4S,5S)-3,4-dihydroxy-5-[(1R,2R)-1,2,3-trihydroxypropyl]tetrahydrofuran-2-one, (3R,4S,5S)-3,4-Dihydroxy-5-[(1R,2R)-1,2,3-trihydroxypropyl]dihydrofuran-2(3H)-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of D -Glucoheptono-1,4-lactone?

The CAS Registry Number of D -Glucoheptono-1,4-lactone is 89-67-8. It is also known as Heptono-1,4-lactone, D-glycero-D-gulo-Heptonic acid, gamma-lactone, (3R,4S,5S)-3,4-dihydroxy-5-((1R,2R)-1,2,3-trihydroxypropyl)dihydrofuran-2(3H)-one.

What is the molecular formula and molecular weight of D -Glucoheptono-1,4-lactone?

D -Glucoheptono-1,4-lactone has the molecular formula C7H12O7 and a molecular weight of 208.17 g/mol. Its IUPAC name is (3R,4S,5S)-3,4-dihydroxy-5-[(1R,2R)-1,2,3-trihydroxypropyl]oxolan-2-one.

What is D -Glucoheptono-1,4-lactone used for?

D -Glucoheptono-1,4-lactone is supplied as a characterised reference material related to Canagliflozin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of D -Glucoheptono-1,4-lactone can I order?

We supply D -Glucoheptono-1,4-lactone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with D -Glucoheptono-1,4-lactone?

Yes. Every lot of D -Glucoheptono-1,4-lactone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can D -Glucoheptono-1,4-lactone be shipped internationally?

Yes. We export D -Glucoheptono-1,4-lactone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.