Manidipine Dihydrochloride

About Manidipine Dihydrochloride

Manidipine Dihydrochloride is a high-purity reference standard of Manidipine carrying the CAS registry number 89226-75-5. The compound has the formula C35H40Cl2N4O6, corresponding to a molecular weight of 683.6 g/mol. Common synonyms include manidipine hydrochloride and Manidipine HCl.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Manidipine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Manidipine Dihydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Manidipine

View every impurity, metabolite and intermediate we list for Manidipine.

Manidipine impurities

Specifications & identifiers

Chemical identifiers
Product name	Manidipine Dihydrochloride
Catalogue No.	VQ-038250
CAS Number	89226-75-5
IUPAC name	5-O-[2-(4-benzhydrylpiperazin-1-yl)ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;dihydrochloride
Molecular formula	C₃₅H₄₀Cl₂N₄O₆
Molecular weight	683.6 g/mol
Exact mass	682.2325
Grade	Reference Standard
HSN code	38229090
InChIKey	JINNGBXKBDUGQT-UHFFFAOYSA-N
SMILES	CC1=C(C(C(=C(N1)C)C(=O)OCCN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC.Cl.Cl
PubChem CID	150762

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 9
TPSA	117 Å²
Synonyms	manidipine hydrochloride, Manidipine HCl, Manidipine 2HCl, Franidipine hydrochloride, Manidipine.2HCl, (+-)-Manidipine hydrochloride, Manidipine hydrochloride (JP18)

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301+H311+H331Toxic if swallowed, in contact with skin or if inhaled
H301Toxic if swallowed
H311Toxic in contact with skin
H331Toxic if inhaled
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P262, P264, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P316, P318, P319, P321, P330, P361 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Manidipine Dihydrochloride?

The CAS Registry Number of Manidipine Dihydrochloride is 89226-75-5. It is also known as manidipine hydrochloride, Manidipine HCl, Manidipine 2HCl.

What is the molecular formula and molecular weight of Manidipine Dihydrochloride?

Manidipine Dihydrochloride has the molecular formula C35H40Cl2N4O6 and a molecular weight of 683.6 g/mol.

What is Manidipine Dihydrochloride used for?

Manidipine Dihydrochloride is supplied as a characterised reference material related to Manidipine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Manidipine Dihydrochloride can I order?

We supply Manidipine Dihydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Manidipine Dihydrochloride?

Yes. Every lot of Manidipine Dihydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Manidipine Dihydrochloride be shipped internationally?

Yes. Manidipine Dihydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.