2′-[Hydroxybiphenyl]-3-carboxylic acid

About 2′-[Hydroxybiphenyl]-3-carboxylic acid

2′-[Hydroxybiphenyl]-3-carboxylic acid is a metabolite or degradation product of Eltrombopag carrying the CAS registry number 893736-72-6. Its molecular formula is C13H10O3 and its molecular weight is 214.22 g/mol. Its systematic (IUPAC) name is 3-(2-hydroxyphenyl)benzoic acid. Alternative names: 2'-Hydroxy[1,1'-biphenyl]-3-carboxylic acid and 2'-Hydroxy(1,1'-biphenyl)-3-carboxylic acid.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Eltrombopag, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 2′-[Hydroxybiphenyl]-3-carboxylic acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Eltrombopag

View every impurity, metabolite and intermediate we list for Eltrombopag.

Eltrombopag impurities

Specifications & identifiers

Chemical identifiers
Product name	2′-[Hydroxybiphenyl]-3-carboxylic acid
Catalogue No.	VQ-025513
CAS Number	893736-72-6
IUPAC name	3-(2-hydroxyphenyl)benzoic acid
Molecular formula	C₁₃H₁₀O₃
Molecular weight	214.22 g/mol
Exact mass	214.063
Grade	Reference Standard
HSN code	38229090
InChIKey	OCZVWZVTEQXRPI-UHFFFAOYSA-N
SMILES	C1=CC=C(C(=C1)C2=CC(=CC=C2)C(=O)O)O
PubChem CID	20100112

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	2 / 3
TPSA	57.5 Å²
Synonyms	2'-Hydroxy[1,1'-biphenyl]-3-carboxylic acid, 2'-Hydroxy(1,1'-biphenyl)-3-carboxylic acid, (1,1'-Biphenyl)-3-carboxylic acid, 2'-hydroxy-, [1,1'-Biphenyl]-3-carboxylic acid, 2'-hydroxy-, 2'-Hydroxy-[1,1'-biphenyl]-3-carboxylic acid, 2'-Hydroxy-[1,1'-biphenyl]-3-carboxylicacid

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2′-[Hydroxybiphenyl]-3-carboxylic acid?

The CAS Registry Number of 2′-[Hydroxybiphenyl]-3-carboxylic acid is 893736-72-6. It is also known as 2'-Hydroxy[1,1'-biphenyl]-3-carboxylic acid, 2'-Hydroxy(1,1'-biphenyl)-3-carboxylic acid, (1,1'-Biphenyl)-3-carboxylic acid, 2'-hydroxy-.

What is the molecular formula and molecular weight of 2′-[Hydroxybiphenyl]-3-carboxylic acid?

2′-[Hydroxybiphenyl]-3-carboxylic acid has the molecular formula C13H10O3 and a molecular weight of 214.22 g/mol. Its IUPAC name is 3-(2-hydroxyphenyl)benzoic acid.

What is 2′-[Hydroxybiphenyl]-3-carboxylic acid used for?

2′-[Hydroxybiphenyl]-3-carboxylic acid is supplied as a characterised reference material related to Eltrombopag. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2′-[Hydroxybiphenyl]-3-carboxylic acid can I order?

We supply 2′-[Hydroxybiphenyl]-3-carboxylic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2′-[Hydroxybiphenyl]-3-carboxylic acid?

Yes. Every lot of 2′-[Hydroxybiphenyl]-3-carboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2′-[Hydroxybiphenyl]-3-carboxylic acid be shipped internationally?

Yes. 2′-[Hydroxybiphenyl]-3-carboxylic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.