Itraconazole Hydroxy Isopropyltriazolone Impu… 89848-19-1

About Itraconazole Hydroxy Isopropyltriazolone Impurity

Itraconazole Hydroxy Isopropyltriazolone Impurity is an impurity of Itraconazole carrying the CAS registry number 89848-19-1. Formula C21H25N5O2, molecular weight 379.5 g/mol. Systematically, it is named 4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-2-propan-2-yl-1,2,4-triazol-3-one. Alternative names: Itraconazole Impurity 25.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Itraconazole to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Itraconazole

View every impurity, metabolite and intermediate we list for Itraconazole.

Itraconazole impurities

Specifications & identifiers

Chemical identifiers
Product name	Itraconazole Hydroxy Isopropyltriazolone Impurity
Catalogue No.	VQ-044387
CAS Number	89848-19-1
IUPAC name	4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-2-propan-2-yl-1,2,4-triazol-3-one
Molecular formula	C₂₁H₂₅N₅O₂
Molecular weight	379.5 g/mol
Exact mass	379.2008
Grade	Reference Standard
HSN code	38229090
InChIKey	QDIXRTOYOSHXMN-UHFFFAOYSA-N
SMILES	CC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)O
PubChem CID	14855351

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	1 / 5
TPSA	62.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Itraconazole Hydroxy Isopropyltriazolone Impurity?

The CAS Registry Number of Itraconazole Hydroxy Isopropyltriazolone Impurity is 89848-19-1. It is also known as Itraconazole Impurity 25, 4-(4-(4-(4-Hydroxyphenyl)piperazin-1-yl)phenyl)-1-isopropyl-1H-1,2,4-triazol-5(4H)-one.

What is the molecular formula and molecular weight of Itraconazole Hydroxy Isopropyltriazolone Impurity?

Itraconazole Hydroxy Isopropyltriazolone Impurity has the molecular formula C21H25N5O2 and a molecular weight of 379.5 g/mol. Its IUPAC name is 4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-2-propan-2-yl-1,2,4-triazol-3-one.

What is Itraconazole Hydroxy Isopropyltriazolone Impurity used for?

Itraconazole Hydroxy Isopropyltriazolone Impurity is supplied as a characterised reference material related to Itraconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Itraconazole Hydroxy Isopropyltriazolone Impurity can I order?

We supply Itraconazole Hydroxy Isopropyltriazolone Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Itraconazole Hydroxy Isopropyltriazolone Impurity?

Yes. Every lot of Itraconazole Hydroxy Isopropyltriazolone Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Itraconazole Hydroxy Isopropyltriazolone Impurity be shipped internationally?

Yes. We export Itraconazole Hydroxy Isopropyltriazolone Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.