Itraconazole N-Desalkyl Impurity

About Itraconazole N-Desalkyl Impurity

Itraconazole N-Desalkyl Impurity is a metabolite or degradation product of Itraconazole carrying the CAS registry number 89848-41-9. Formula C31H30Cl2N8O4, molecular weight 649.5 g/mol. Alternative names: Itraconazole N-Desalky Impurity and N-Desalkyl Itraconazole.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Itraconazole, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Itraconazole

View every impurity, metabolite and intermediate we list for Itraconazole.

Itraconazole impurities

Specifications & identifiers

Chemical identifiers
Product name	Itraconazole N-Desalkyl Impurity
Catalogue No.	VQ-026256
CAS Number	89848-41-9
IUPAC name	4-[4-[4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1H-1,2,4-triazol-5-one
Molecular formula	C₃₁H₃₀Cl₂N₈O₄
Molecular weight	649.5 g/mol
Exact mass	648.1767
Grade	Reference Standard
HSN code	38229090
InChIKey	FBAPZOQKYAPBHI-DLFZDVPBSA-N
SMILES	C1CN(CCN1C2=CC=C(C=C2)N3C=NNC3=O)C4=CC=C(C=C4)OC[C@@H]5CO[C@@](O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl
PubChem CID	53789808

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	1 / 9
TPSA	110 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Itraconazole N-Desalkyl Impurity?

The CAS Registry Number of Itraconazole N-Desalkyl Impurity is 89848-41-9. It is also known as Itraconazole N-Desalky Impurity, N-Desalkyl Itraconazole.

What is the molecular formula and molecular weight of Itraconazole N-Desalkyl Impurity?

Itraconazole N-Desalkyl Impurity has the molecular formula C31H30Cl2N8O4 and a molecular weight of 649.5 g/mol. Its IUPAC name is 4-[4-[4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1H-1,2,4-triazol-5-one.

What is Itraconazole N-Desalkyl Impurity used for?

Itraconazole N-Desalkyl Impurity is supplied as a characterised reference material related to Itraconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Itraconazole N-Desalkyl Impurity can I order?

We supply Itraconazole N-Desalkyl Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Itraconazole N-Desalkyl Impurity?

Yes. Every lot of Itraconazole N-Desalkyl Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Itraconazole N-Desalkyl Impurity be shipped internationally?

Yes. We export Itraconazole N-Desalkyl Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.