Crisaborole

About Crisaborole

Crisaborole is a high-purity reference standard of Crisaborole carrying the CAS registry number 906673-24-3. The compound has the formula C14H10BNO3, corresponding to a molecular weight of 251.05 g/mol. The IUPAC name is 4-[(1-hydroxy-3H-2,1-benzoxaborol-5-yl)oxy]benzonitrile. Common synonyms include crisaborol and Crisaborole (AN2728).

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Crisaborole, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Crisaborole is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Crisaborole

View every impurity, metabolite and intermediate we list for Crisaborole.

Crisaborole impurities

Specifications & identifiers

Chemical identifiers
Product name	Crisaborole
Catalogue No.	VQ-029933
CAS Number	906673-24-3
IUPAC name	4-[(1-hydroxy-3H-2,1-benzoxaborol-5-yl)oxy]benzonitrile
Molecular formula	C₁₄H₁₀BNO₃
Molecular weight	251.05 g/mol
Exact mass	251.0754
Grade	Reference Standard
HSN code	38229090
InChIKey	USZAGAREISWJDP-UHFFFAOYSA-N
SMILES	B1(C2=C(CO1)C=C(C=C2)OC3=CC=C(C=C3)C#N)O
PubChem CID	44591583

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 4
TPSA	62.5 Å²
Synonyms	crisaborol, 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]benzonitrile, 4-((1-Hydroxy-1,3-dihydrobenzo(c)(1,2)oxaborol-6-yl)oxy)benzonitrile, Benzonitrile, 4-((1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy)-, 4-((1-hydroxy-3H-2,1-benzoxaborol-5-yl)oxy)benzonitrile, 4-((1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy)benzonitrile, 4-((1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)oxy)benzonitrile, 5-(4-cyanophenoxy)-2,3-dihydro-1-hydroxy-2,1-benzoxaborole, Crisaborole (AN2728), 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]benzonitrile, 4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile, 4-[(1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)oxy]benzonitrile

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Crisaborole?

The CAS Registry Number of Crisaborole is 906673-24-3. It is also known as crisaborol, 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]benzonitrile, 4-((1-Hydroxy-1,3-dihydrobenzo(c)(1,2)oxaborol-6-yl)oxy)benzonitrile.

What is the molecular formula and molecular weight of Crisaborole?

Crisaborole has the molecular formula C14H10BNO3 and a molecular weight of 251.05 g/mol. Its IUPAC name is 4-[(1-hydroxy-3H-2,1-benzoxaborol-5-yl)oxy]benzonitrile.

What is Crisaborole used for?

Crisaborole is supplied as a characterised reference material related to Crisaborole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Crisaborole can I order?

We supply Crisaborole in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Crisaborole?

Yes. Every lot of Crisaborole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Crisaborole be shipped internationally?

Yes. Crisaborole is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.