Metacycline

Name: Metacycline
Brand: Vaqora Chemicals
SKU: VQ-025404

About Metacycline

Metacycline is an impurity of Methacycline carrying the CAS registry number 914-00-1. Its molecular formula is C22H22N2O8 and its molecular weight is 442.4 g/mol. Common synonyms include Methacycline and Rondomycin.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Methacycline to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Metacycline in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Methacycline

View every impurity, metabolite and intermediate we list for Methacycline.

Methacycline impurities

Specifications & identifiers

Chemical identifiers
Product name	Metacycline
Catalogue No.	VQ-025404
CAS Number	914-00-1
IUPAC name	(4S,4aR,5S,5aR,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methylidene-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
Molecular formula	C₂₂H₂₂N₂O₈
Molecular weight	442.4 g/mol
Exact mass	442.1376
Grade	Reference Standard
HSN code	38229090
InChIKey	XIYOPDCBBDCGOE-IWVLMIASSA-N
SMILES	CN(C)[C@H]1[C@@H]2[C@H]([C@@H]3C(=C)C4=C(C(=CC=C4)O)C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O
PubChem CID	54675785

Physical properties
Physical form	Solid
LogP (XLogP3)	0.3
H-bond donors / acceptors	6 / 9
TPSA	182 Å²
Synonyms	Methacycline, Rondomycin, Methylenecycline, Tri-methacycline, 6-Methylene-5-hydroxytetracycline, 6-Methylene-5-oxytetracycline, 6-Methyleneoxytetracycline, 6-Deoxy-6-demethyl-6-methylene-5-oxytetracycline, 6-Demethyl-6-deoxy-5-hydroxy-6-methylenetetracycline, Methacycline base, Methacycline amphoteric, Methacycline (USAN)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Metacycline?

The CAS Registry Number of Metacycline is 914-00-1. It is also known as Methacycline, Rondomycin, Methylenecycline.

What is the molecular formula and molecular weight of Metacycline?

Metacycline has the molecular formula C22H22N2O8 and a molecular weight of 442.4 g/mol. Its IUPAC name is (4S,4aR,5S,5aR,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methylidene-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide.

What is Metacycline used for?

Metacycline is supplied as a characterised reference material related to Methacycline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Metacycline can I order?

We supply Metacycline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Metacycline?

Yes. Every lot of Metacycline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Metacycline be shipped internationally?

Yes. We export Metacycline worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.