4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one

Name: 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one
Brand: Vaqora Chemicals
SKU: VQ-027152

About 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one

Vaqora Chemicals supplies 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one, a metabolite or degradation product of Azilsartan registered under CAS number 91526-18-0. With the molecular formula C5H6O4, it has a molar mass of 130.1 g/mol. It is also known as 1,3-Dioxol-2-one, 4-(hydroxymethyl)-5-methyl- or 5-methyl-4-hydroxymethyl-2-oxo-1,3-dioxolene.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Azilsartan, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Azilsartan

View every impurity, metabolite and intermediate we list for Azilsartan.

Azilsartan impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one
Catalogue No.	VQ-027152
CAS Number	91526-18-0
IUPAC name	4-(hydroxymethyl)-5-methyl-1,3-dioxol-2-one
Molecular formula	C₅H₆O₄
Molecular weight	130.1 g/mol
Exact mass	130.0266
Grade	Reference Standard
HSN code	38229090
InChIKey	JEQSUJXHFAXJOW-UHFFFAOYSA-N
SMILES	CC1=C(OC(=O)O1)CO
PubChem CID	10510878

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.2
H-bond donors / acceptors	1 / 4
TPSA	55.8 Å²
Synonyms	1,3-Dioxol-2-one, 4-(hydroxymethyl)-5-methyl-, 5-methyl-4-hydroxymethyl-2-oxo-1,3-dioxolene, (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl alcohol, 4-(hydroxymethyl)-5-methyl-2H-1,3-dioxol-2-one, Olmesartan metabolite RNH-8097, (5-Methyl-2-oxo-1,3-dioxol-4-yl)methanol, 4-hydroxymethyl-5-methyl-2-oxo-1,3-dioxole

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one?

The CAS Registry Number of 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one is 91526-18-0. It is also known as 1,3-Dioxol-2-one, 4-(hydroxymethyl)-5-methyl-, 5-methyl-4-hydroxymethyl-2-oxo-1,3-dioxolene, (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl alcohol.

What is the molecular formula and molecular weight of 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one?

4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one has the molecular formula C5H6O4 and a molecular weight of 130.1 g/mol. Its IUPAC name is 4-(hydroxymethyl)-5-methyl-1,3-dioxol-2-one.

What is 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one used for?

4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one is supplied as a characterised reference material related to Azilsartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one can I order?

We supply 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one?

Yes. Every lot of 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one be shipped internationally?

Yes. 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.