1,1,3-Trichloroacetone

Name: 1,1,3-Trichloroacetone
Brand: Vaqora Chemicals
SKU: VQ-039395

About 1,1,3-Trichloroacetone

Vaqora Chemicals supplies 1,1,3-Trichloroacetone, a process intermediate or related compound of N methylpyrrolidone registered under CAS number 921-03-9. With the molecular formula C3H3Cl3O, it has a molar mass of 161.41 g/mol. Systematically, it is named 1,1,3-trichloropropan-2-one. It is also known as 1,1,3-Trichloro-2-propanone or 2-Propanone, 1,1,3-trichloro-.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to N methylpyrrolidone, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to N methylpyrrolidone

View every impurity, metabolite and intermediate we list for N methylpyrrolidone.

N methylpyrrolidone impurities

Specifications & identifiers

Chemical identifiers
Product name	1,1,3-Trichloroacetone
Catalogue No.	VQ-039395
CAS Number	921-03-9
IUPAC name	1,1,3-trichloropropan-2-one
Molecular formula	C₃H₃Cl₃O
Molecular weight	161.41 g/mol
Exact mass	159.9249
InChIKey	ZWILTCXCTVMANU-UHFFFAOYSA-N
SMILES	C(C(=O)C(Cl)Cl)Cl
PubChem CID	13530

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	0 / 1
TPSA	17.1 Å²
Synonyms	1,1,3-Trichloro-2-propanone, 2-Propanone, 1,1,3-trichloro-, alpha,alpha',alpha'-Trichloroacetone, 1,1,3-Trichloropropanone, .alpha.,.alpha.',.alpha.'-Trichloroacetone, 1,1,3-Trichloroacetone 1,1,3-TCA

Safety & hazard information (GHS)

Corrosive

Toxic

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H314Causes severe skin burns and eye damage
H330Fatal if inhaled
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P260, P264, P270, P271, P273, P280, P284, P301 + P316, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P320, P321, P330, P363, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1,1,3-Trichloroacetone?

The CAS Registry Number of 1,1,3-Trichloroacetone is 921-03-9. It is also known as 1,1,3-Trichloro-2-propanone, 2-Propanone, 1,1,3-trichloro-, alpha,alpha',alpha'-Trichloroacetone.

What is the molecular formula and molecular weight of 1,1,3-Trichloroacetone?

1,1,3-Trichloroacetone has the molecular formula C3H3Cl3O and a molecular weight of 161.41 g/mol. Its IUPAC name is 1,1,3-trichloropropan-2-one.

What is 1,1,3-Trichloroacetone used for?

1,1,3-Trichloroacetone is supplied as a characterised reference material related to N methylpyrrolidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1,1,3-Trichloroacetone can I order?

We supply 1,1,3-Trichloroacetone, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1,1,3-Trichloroacetone?

Yes. Every lot of 1,1,3-Trichloroacetone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1,1,3-Trichloroacetone be shipped internationally?

Yes. 1,1,3-Trichloroacetone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.