N-Nitroso-Trimetazidine

Name: N-Nitroso-Trimetazidine
Brand: Vaqora Chemicals
SKU: VQ-028533

About N-Nitroso-Trimetazidine

Vaqora Chemicals supplies N-Nitroso-Trimetazidine, a nitrosamine impurity of Trimetazidine registered under CAS number 92432-50-3. Formula C14H21N3O4, molecular weight 295.33 g/mol. Its systematic (IUPAC) name is 1-nitroso-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine. Common synonyms include N-Nitroso Trimetazidine (Free Base).

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 5 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer N-Nitroso-Trimetazidine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Trimetazidine

View every impurity, metabolite and intermediate we list for Trimetazidine.

Trimetazidine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso-Trimetazidine
Catalogue No.	VQ-028533
CAS Number	92432-50-3
IUPAC name	1-nitroso-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine
Molecular formula	C₁₄H₂₁N₃O₄
Molecular weight	295.33 g/mol
Exact mass	295.1532
Grade	Reference Standard
HSN code	38229090
InChIKey	NFINNRJTHOYASP-UHFFFAOYSA-N
SMILES	COC1=C(C(=C(C=C1)CN2CCN(CC2)N=O)OC)OC
PubChem CID	168229397

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	0 / 7
TPSA	63.6 Å²

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H351Suspected of causing cancer
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P318, P319, P321, P330, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso-Trimetazidine?

The CAS Registry Number of N-Nitroso-Trimetazidine is 92432-50-3. It is also known as 1-Nitroso-4-(2,3,4-trimethoxy-benzyl)-piperazine, N-Nitroso Trimetazidine (Free Base), 1-nitroso-4-((2,3,4-trimethoxyphenyl)methyl)piperazine.

What is the molecular formula and molecular weight of N-Nitroso-Trimetazidine?

N-Nitroso-Trimetazidine has the molecular formula C14H21N3O4 and a molecular weight of 295.33 g/mol. Its IUPAC name is 1-nitroso-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine.

What is N-Nitroso-Trimetazidine used for?

N-Nitroso-Trimetazidine is supplied as a characterised reference material related to Trimetazidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso-Trimetazidine can I order?

We supply N-Nitroso-Trimetazidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso-Trimetazidine?

Yes. Every lot of N-Nitroso-Trimetazidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso-Trimetazidine be shipped internationally?

Yes. N-Nitroso-Trimetazidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.