Annamycin

Name: Annamycin
Brand: Vaqora Chemicals
SKU: VQ-045242

About Annamycin

Listed under CAS 92689-49-1, Annamycin is an API impurity reference standard available from Vaqora Chemicals. Formula C26H25IO11, molecular weight 640.4 g/mol. Alternative names: Naxtarubicin and Naxtarubicin (USAN).

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of the parent drug substance to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Annamycin in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Specifications & identifiers

Chemical identifiers
Product name	Annamycin
Catalogue No.	VQ-045242
CAS Number	92689-49-1
IUPAC name	(7S,9S)-7-[(2R,3R,4R,5R,6S)-4,5-dihydroxy-3-iodo-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-8,10-dihydro-7H-tetracene-5,12-dione
Molecular formula	C₂₆H₂₅IO₁₁
Molecular weight	640.4 g/mol
Exact mass	640.0442
Grade	Reference Standard
HSN code	38229090
InChIKey	CIDNKDMVSINJCG-GKXONYSUSA-N
SMILES	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)CO)O)I)O)O
PubChem CID	115212

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	6 / 11
TPSA	191 Å²
Synonyms	Naxtarubicin, 2'-Iodo-3'-hydroxy-4'-epi-4-demethoxydoxorubicin, Naxtarubicin (USAN), Naxtarubicine, AR-522

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H340May cause genetic defects
H350May cause cancer
H360May damage fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Annamycin?

The CAS Registry Number of Annamycin is 92689-49-1. It is also known as Naxtarubicin, 2'-Iodo-3'-hydroxy-4'-epi-4-demethoxydoxorubicin, Naxtarubicin (USAN).

What is the molecular formula and molecular weight of Annamycin?

Annamycin has the molecular formula C26H25IO11 and a molecular weight of 640.4 g/mol. Its IUPAC name is (7S,9S)-7-[(2R,3R,4R,5R,6S)-4,5-dihydroxy-3-iodo-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-8,10-dihydro-7H-tetracene-5,12-dione.

Which grade and pack sizes of Annamycin can I order?

We supply Annamycin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Annamycin?

Yes. Every lot of Annamycin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Annamycin be shipped internationally?

Yes. Annamycin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.