Gefapixant Nitrile Impurity

Name: Gefapixant Nitrile Impurity
Brand: Vaqora Chemicals
SKU: VQ-030952

About Gefapixant Nitrile Impurity

Gefapixant Nitrile Impurity (CAS 927872-64-8) is an impurity of Gefapixant offered by Vaqora Chemicals. The compound has the formula C12H15NO2, corresponding to a molecular weight of 205.25 g/mol. Its systematic (IUPAC) name is 2-(4-methoxy-2-propan-2-ylphenoxy)acetonitrile. Alternative names: Gefapixant Impurity 12 and (2-Isopropyl-4-methoxy-phenoxy)-acetonitrile.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Gefapixant to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Gefapixant Nitrile Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Gefapixant

View every impurity, metabolite and intermediate we list for Gefapixant.

Gefapixant impurities

Specifications & identifiers

Chemical identifiers
Product name	Gefapixant Nitrile Impurity
Catalogue No.	VQ-030952
CAS Number	927872-64-8
IUPAC name	2-(4-methoxy-2-propan-2-ylphenoxy)acetonitrile
Molecular formula	C₁₂H₁₅NO₂
Molecular weight	205.25 g/mol
Exact mass	205.1103
Grade	Reference Standard
HSN code	38229090
InChIKey	VYWGSKTVJRQMBI-UHFFFAOYSA-N
SMILES	CC(C)C1=C(C=CC(=C1)OC)OCC#N
PubChem CID	25241771

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	0 / 3
TPSA	42.3 Å²
Synonyms	Acetonitrile, 2-[4-methoxy-2-(1-methylethyl)phenoxy]-, 2-[4-methoxy-2-(propan-2-yl)phenoxy]acetonitrile, Gefapixant Impurity 12, (2-Isopropyl-4-methoxy-phenoxy)-acetonitrile, 2-(2-Isopropyl-4-methoxy-phenoxy)acetonitrile, [4-Methoxy-2-(propan-2-yl)phenoxy]acetonitrile

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Gefapixant Nitrile Impurity?

The CAS Registry Number of Gefapixant Nitrile Impurity is 927872-64-8. It is also known as Acetonitrile, 2-[4-methoxy-2-(1-methylethyl)phenoxy]-, 2-[4-methoxy-2-(propan-2-yl)phenoxy]acetonitrile, Gefapixant Impurity 12.

What is the molecular formula and molecular weight of Gefapixant Nitrile Impurity?

Gefapixant Nitrile Impurity has the molecular formula C12H15NO2 and a molecular weight of 205.25 g/mol. Its IUPAC name is 2-(4-methoxy-2-propan-2-ylphenoxy)acetonitrile.

What is Gefapixant Nitrile Impurity used for?

Gefapixant Nitrile Impurity is supplied as a characterised reference material related to Gefapixant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Gefapixant Nitrile Impurity can I order?

We supply Gefapixant Nitrile Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Gefapixant Nitrile Impurity?

Yes. Every lot of Gefapixant Nitrile Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Gefapixant Nitrile Impurity be shipped internationally?

Yes. We export Gefapixant Nitrile Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.