Difamilast

About Difamilast

Difamilast is a high-purity reference standard of Difamilast carrying the CAS registry number 937782-05-3. The compound has the formula C23H24F2N2O5, corresponding to a molecular weight of 446.4 g/mol. Its systematic (IUPAC) name is N-[[2-[4-(difluoromethoxy)-3-propan-2-yloxyphenyl]-1,3-oxazol-4-yl]methyl]-2-ethoxybenzamide. Common synonyms include Difamilast (JAN/USAN) and EX-A7792.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this Difamilast standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Difamilast is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Difamilast

View every impurity, metabolite and intermediate we list for Difamilast.

Difamilast impurities

Specifications & identifiers

Chemical identifiers
Product name	Difamilast
Catalogue No.	VQ-030194
CAS Number	937782-05-3
IUPAC name	N-[[2-[4-(difluoromethoxy)-3-propan-2-yloxyphenyl]-1,3-oxazol-4-yl]methyl]-2-ethoxybenzamide
Molecular formula	C₂₃H₂₄F₂N₂O₅
Molecular weight	446.4 g/mol
Exact mass	446.1653
Grade	Reference Standard
HSN code	38229090
InChIKey	VFBILHPIHUPBPZ-UHFFFAOYSA-N
SMILES	CCOC1=CC=CC=C1C(=O)NCC2=COC(=N2)C3=CC(=C(C=C3)OC(F)F)OC(C)C
PubChem CID	57855696

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	1 / 8
TPSA	82.8 Å²
Synonyms	Difamilast (JAN/USAN), N-[[2-[4-(Difluoromethoxy)-3-(1-methylethoxy)phenyl]-4-oxazolyl]methyl]-2-ethoxybenzamide, N-[2-(4-difluoromethoxy-3-isopropoxyphenyl)oxazol-4-ylmethyl]-2-ethoxybenzamide, EX-A7792, example 352 [WO2007058338], N-[[2-[4-(difluoromethoxy)-3-isopropoxy-phenyl]oxazol-4-yl]methyl]-2-ethoxy-benzamide, N-[[2-[4-(Difluoromethoxy)-3-isopropoxyphenyl]-4-oxazolyl]methyl]-2-ethoxybenzamide

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Difamilast?

The CAS Registry Number of Difamilast is 937782-05-3. It is also known as Difamilast (JAN/USAN), N-[[2-[4-(Difluoromethoxy)-3-(1-methylethoxy)phenyl]-4-oxazolyl]methyl]-2-ethoxybenzamide, N-[2-(4-difluoromethoxy-3-isopropoxyphenyl)oxazol-4-ylmethyl]-2-ethoxybenzamide.

What is the molecular formula and molecular weight of Difamilast?

Difamilast has the molecular formula C23H24F2N2O5 and a molecular weight of 446.4 g/mol. Its IUPAC name is N-[[2-[4-(difluoromethoxy)-3-propan-2-yloxyphenyl]-1,3-oxazol-4-yl]methyl]-2-ethoxybenzamide.

What is Difamilast used for?

Difamilast is supplied as a characterised reference material related to Difamilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Difamilast can I order?

We supply Difamilast in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Difamilast?

Yes. Every lot of Difamilast is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Difamilast be shipped internationally?

Yes. We export Difamilast worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.