Isavuconazonium Sulfate

About Isavuconazonium Sulfate

Isavuconazonium Sulfate is an impurity of Isavuconazole carrying the CAS registry number 946075-13-4. Formula C35H36F2N8O9S2, molecular weight 814.8 g/mol. Common synonyms include EX-A1786 and Isavuconazonium sulfate (JAN/USAN).

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 7 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Isavuconazole to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Isavuconazole

View every impurity, metabolite and intermediate we list for Isavuconazole.

Isavuconazole impurities

Specifications & identifiers

Chemical identifiers
Product name	Isavuconazonium Sulfate
Catalogue No.	VQ-026227
CAS Number	946075-13-4
IUPAC name	[2-[1-[1-[(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-1,2,4-triazol-4-ium-4-yl]ethoxycarbonyl-methylamino]-3-pyridinyl]methyl 2-(methylamino)acetate;hydrogen sulfate
Molecular formula	C₃₅H₃₆F₂N₈O₉S₂
Molecular weight	814.8 g/mol
Exact mass	814.2015
Grade	Reference Standard
HSN code	38229090
InChIKey	LWXUIUUOMSMZKJ-KLFWAVJMSA-M
SMILES	C[C@@H](C1=NC(=CS1)C2=CC=C(C=C2)C#N)[C@](CN3C=[N+](C=N3)C(C)OC(=O)N(C)C4=C(C=CC=N4)COC(=O)CNC)(C5=C(C=CC(=C5)F)F)O.OS(=O)(=O)[O-]
PubChem CID	72196309

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 17
TPSA	273 Å²

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Isavuconazonium Sulfate?

The CAS Registry Number of Isavuconazonium Sulfate is 946075-13-4. It is also known as EX-A1786, Isavuconazonium sulfate (JAN/USAN).

What is the molecular formula and molecular weight of Isavuconazonium Sulfate?

Isavuconazonium Sulfate has the molecular formula C35H36F2N8O9S2 and a molecular weight of 814.8 g/mol.

What is Isavuconazonium Sulfate used for?

Isavuconazonium Sulfate is supplied as a characterised reference material related to Isavuconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Isavuconazonium Sulfate can I order?

We supply Isavuconazonium Sulfate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Isavuconazonium Sulfate?

Yes. Every lot of Isavuconazonium Sulfate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Isavuconazonium Sulfate be shipped internationally?

Yes. Isavuconazonium Sulfate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.