22,23-Dihydroavermectin B1(a)

Name: 22,23-Dihydroavermectin B1(a)
Brand: Vaqora Chemicals
SKU: VQ-037796

About 22,23-Dihydroavermectin B1(a)

Vaqora Chemicals supplies 22,23-Dihydroavermectin B1(a), an impurity of Avermectin registered under CAS number 94837-49-7. Its molecular formula is C48H75O17P and its molecular weight is 955.1 g/mol. It is also known as 22,23-Dihydro-5-O-demethylavermectin A1a or H2B1a avermectin.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Avermectin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 22,23-Dihydroavermectin B1(a) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Avermectin

View every impurity, metabolite and intermediate we list for Avermectin.

Avermectin impurities

Specifications & identifiers

Chemical identifiers
Product name	22,23-Dihydroavermectin B1(a)
Catalogue No.	VQ-037796
CAS Number	94837-49-7
IUPAC name	[(2S,3S,4S,6S)-6-[(2S,3S,4S,6R)-6-[(1R,4S,5'S,6R,6'R,8R,10E,12R,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-5',11,13,22-tetramethyl-2-oxospiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-12-yl]oxy-4-methoxy-2-methyloxan-3-yl]oxy-4-methoxy-2-methyloxan-3-yl] dihydrogen phosphate
Molecular formula	C₄₈H₇₅O₁₇P
Molecular weight	955.1 g/mol
Exact mass	954.4742
Grade	Reference Standard
HSN code	38229090
InChIKey	AHBNYVFRDZDQBZ-NUEMJPNFSA-N
SMILES	CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)OP(=O)(O)O)OC)OC)\C)C
PubChem CID	6444090

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	4 / 17
TPSA	217 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 22,23-Dihydroavermectin B1(a)?

The CAS Registry Number of 22,23-Dihydroavermectin B1(a) is 94837-49-7. It is also known as 22,23-Dihydro-5-O-demethylavermectin A1a, H2B1a avermectin, Dihydroivermectin B1a.

What is the molecular formula and molecular weight of 22,23-Dihydroavermectin B1(a)?

22,23-Dihydroavermectin B1(a) has the molecular formula C48H75O17P and a molecular weight of 955.1 g/mol.

What is 22,23-Dihydroavermectin B1(a) used for?

22,23-Dihydroavermectin B1(a) is supplied as a characterised reference material related to Avermectin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 22,23-Dihydroavermectin B1(a) can I order?

We supply 22,23-Dihydroavermectin B1(a) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 22,23-Dihydroavermectin B1(a)?

Yes. Every lot of 22,23-Dihydroavermectin B1(a) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 22,23-Dihydroavermectin B1(a) be shipped internationally?

Yes. We export 22,23-Dihydroavermectin B1(a) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.