Methyl 2-(3,5-bis(trifluoromethyl)phenyl)acet… 95299-16-4

About Methyl 2-(3,5-bis(trifluoromethyl)phenyl)acetate

Methyl 2-(3,5-bis(trifluoromethyl)phenyl)acetate is an impurity of Netupitant carrying the CAS registry number 95299-16-4. With the molecular formula C11H8F6O2, it has a molar mass of 286.17 g/mol. It is also known as Methyl 3,5-bis(trifluoromethyl)phenylacetate or Methyl 3,5-Bis(trifluoromethyl)benzeneacetate.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Netupitant impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Methyl 2-(3,5-bis(trifluoromethyl)phenyl)acetate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Netupitant

View every impurity, metabolite and intermediate we list for Netupitant.

Netupitant impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl 2-(3,5-bis(trifluoromethyl)phenyl)acetate
Catalogue No.	VQ-049216
CAS Number	95299-16-4
IUPAC name	methyl 2-[3,5-bis(trifluoromethyl)phenyl]acetate
Molecular formula	C₁₁H₈F₆O₂
Molecular weight	286.17 g/mol
Exact mass	286.0428
Grade	Reference Standard
HSN code	38229090
InChIKey	URDXSDHDNSBKHI-UHFFFAOYSA-N
SMILES	COC(=O)CC1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F
PubChem CID	10401718

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	0 / 8
TPSA	26.3 Å²
Synonyms	Benzeneacetic acid, 3,5-bis(trifluoromethyl)-, methyl ester, 3,5-Bis(trifluoromethyl)-benzeneacetic acid methyl ester, 3,5-Bis(trifluoromethyl)phenyl acetic acid methyl ester, Methyl 3,5-bis(trifluoromethyl)phenylacetate, Methyl 3,5-Bis(trifluoromethyl)benzeneacetate, 3,5-bis-trifluoromethylphenylacetic acid methyl ester, methyl 3,5-bis(triflouromethyl)phenylacetate, Methyl 2-(3,5-ditrifluoromethylphenyl)acetate, methyl [3,5-bis(trifluoromethyl)phenyl]acetate, 3,5-Bis(trifluoromethyl)phenylaceticacidmethylester, 3,5-Bis(trifluoromethyl)phenylacetic acid methyl ester

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl 2-(3,5-bis(trifluoromethyl)phenyl)acetate?

The CAS Registry Number of Methyl 2-(3,5-bis(trifluoromethyl)phenyl)acetate is 95299-16-4. It is also known as Benzeneacetic acid, 3,5-bis(trifluoromethyl)-, methyl ester, 3,5-Bis(trifluoromethyl)-benzeneacetic acid methyl ester, 3,5-Bis(trifluoromethyl)phenyl acetic acid methyl ester.

What is the molecular formula and molecular weight of Methyl 2-(3,5-bis(trifluoromethyl)phenyl)acetate?

Methyl 2-(3,5-bis(trifluoromethyl)phenyl)acetate has the molecular formula C11H8F6O2 and a molecular weight of 286.17 g/mol. Its IUPAC name is methyl 2-[3,5-bis(trifluoromethyl)phenyl]acetate.

What is Methyl 2-(3,5-bis(trifluoromethyl)phenyl)acetate used for?

Methyl 2-(3,5-bis(trifluoromethyl)phenyl)acetate is supplied as a characterised reference material related to Netupitant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl 2-(3,5-bis(trifluoromethyl)phenyl)acetate can I order?

We supply Methyl 2-(3,5-bis(trifluoromethyl)phenyl)acetate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl 2-(3,5-bis(trifluoromethyl)phenyl)acetate?

Yes. Every lot of Methyl 2-(3,5-bis(trifluoromethyl)phenyl)acetate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl 2-(3,5-bis(trifluoromethyl)phenyl)acetate be shipped internationally?

Yes. Methyl 2-(3,5-bis(trifluoromethyl)phenyl)acetate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.