6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic… 958457-83-5

About 6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid

6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid is an impurity of Avatrombopag carrying the CAS registry number 958457-83-5. The compound has the formula C12H13ClN2O4, corresponding to a molecular weight of 284.69 g/mol. Systematically, it is named 6-(4-carboxypiperidin-1-yl)-5-chloropyridine-3-carboxylic acid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Avatrombopag to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Avatrombopag

View every impurity, metabolite and intermediate we list for Avatrombopag.

Avatrombopag impurities

Specifications & identifiers

Chemical identifiers
Product name	6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid
Catalogue No.	VQ-021684
CAS Number	958457-83-5
IUPAC name	6-(4-carboxypiperidin-1-yl)-5-chloropyridine-3-carboxylic acid
Molecular formula	C₁₂H₁₃ClN₂O₄
Molecular weight	284.69 g/mol
Exact mass	284.0564
Grade	Reference Standard
HSN code	38229090
InChIKey	GLQRQGIFEOBSFP-UHFFFAOYSA-N
SMILES	C1CN(CCC1C(=O)O)C2=C(C=C(C=N2)C(=O)O)Cl
PubChem CID	138958641

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	2 / 6
TPSA	90.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid?

The CAS Registry Number of 6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid is 958457-83-5. It is also known as 6-(4-Carboxy-1-piperidinyl)-5-chloro-3-pyridinecarboxylic Acid, 3-Pyridinecarboxylic acid, 6-(4-carboxy-1-piperidinyl)-5-chloro-.

What is the molecular formula and molecular weight of 6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid?

6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid has the molecular formula C12H13ClN2O4 and a molecular weight of 284.69 g/mol. Its IUPAC name is 6-(4-carboxypiperidin-1-yl)-5-chloropyridine-3-carboxylic acid.

What is 6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid used for?

6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid is supplied as a characterised reference material related to Avatrombopag. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid can I order?

We supply 6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid?

Yes. Every lot of 6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid be shipped internationally?

Yes. We export 6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.