1-Nitroso-1H-indazole-3-carbonitrile

About 1-Nitroso-1H-indazole-3-carbonitrile

1-Nitroso-1H-indazole-3-carbonitrile is a nitrosamine impurity of Granisetron carrying the CAS registry number 98556-68-4. Its molecular formula is C8H4N4O and its molecular weight is 172.14 g/mol. The IUPAC name is 1-nitrosoindazole-3-carbonitrile.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Granisetron, method validation (AMV) and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 1-Nitroso-1H-indazole-3-carbonitrile is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Granisetron

View every impurity, metabolite and intermediate we list for Granisetron.

Granisetron impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Nitroso-1H-indazole-3-carbonitrile
Catalogue No.	VQ-035228
CAS Number	98556-68-4
IUPAC name	1-nitrosoindazole-3-carbonitrile
Molecular formula	C₈H₄N₄O
Molecular weight	172.14 g/mol
Exact mass	172.0385
Grade	Reference Standard
HSN code	38229090
InChIKey	XZMMRIYVTPHWHW-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C(=NN2N=O)C#N
PubChem CID	119095189

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	0 / 4
TPSA	71 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Nitroso-1H-indazole-3-carbonitrile?

The CAS Registry Number of 1-Nitroso-1H-indazole-3-carbonitrile is 98556-68-4.

What is the molecular formula and molecular weight of 1-Nitroso-1H-indazole-3-carbonitrile?

1-Nitroso-1H-indazole-3-carbonitrile has the molecular formula C8H4N4O and a molecular weight of 172.14 g/mol. Its IUPAC name is 1-nitrosoindazole-3-carbonitrile.

What is 1-Nitroso-1H-indazole-3-carbonitrile used for?

1-Nitroso-1H-indazole-3-carbonitrile is supplied as a characterised reference material related to Granisetron. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Nitroso-1H-indazole-3-carbonitrile can I order?

We supply 1-Nitroso-1H-indazole-3-carbonitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Nitroso-1H-indazole-3-carbonitrile?

Yes. Every lot of 1-Nitroso-1H-indazole-3-carbonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Nitroso-1H-indazole-3-carbonitrile be shipped internationally?

Yes. We export 1-Nitroso-1H-indazole-3-carbonitrile worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.