![(4-(1-(3-(Cyanomethyl)-1-(ethylsulfonyl)azetidin-3-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl Pivalate chemical structure](/media/structures/WENIISNHSRPUOW-UHFFFAOYSA-N.svg)
(4-(1-(3-(Cyanomethyl)-1-(ethylsulfonyl)azetidin-3-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl Pivalate
- CAS
- 1187595-90-9
- Formula
- C22H27N7O4S
- MW
- 485.6 g/mol
VQ-024499
Impurity reference standards
Baricitinib impurities & reference standards
Characterised Baricitinib impurities, degradation products and related compounds for analytical method development, validation, QC release and regulatory filings.
46reference materials
1nitrosamine impurities
2isotope-labelled
COAHPLC · NMR · MS on request
Parent API: Baricitinib WS
1187594-09-7 · C16H17N7O2S
![(4-(1-(3-(Cyanomethyl)azetidin-3-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl Pivalate chemical structure](/media/structures/WYPSYJDXVKDEHX-UHFFFAOYSA-N.svg)
(4-(1-(3-(Cyanomethyl)azetidin-3-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl Pivalate
- CAS
- 2102104-38-9
- Formula
- C20H23N7O2
- MW
- 393.4 g/mol
VQ-044692
1-(1-Ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
- CAS
- 1029716-44-6
- Formula
- C13H23BN2O3
- MW
- 266.15 g/mol
VQ-027954
2-(1-(Ethylsulfonyl)azetidin-3-ylidene)acetonitrile
- CAS
- 1187595-85-2
- Formula
- C7H10N2O2S
- MW
- 186.23 g/mol
VQ-024496
![2-(3-(4-(1-(3-(Cyanomethyl)-1-(ethylsulfonyl)azetidin-3-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile chemical structure](/media/structures/JHFMCKHJCXIHNR-UHFFFAOYSA-N.svg)
2-(3-(4-(1-(3-(Cyanomethyl)-1-(ethylsulfonyl)azetidin-3-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile
- CAS
- 2402776-84-3
- Formula
- C23H27N9O4S2
- MW
- 557.7 g/mol
VQ-029354
![2-(3-(4-(7H-[4,7'-Bipyrrolo[2,3-d]pyrimidin]-4'-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile chemical structure](/media/structures/VQLDZYHZBDVCHK-UHFFFAOYSA-N.svg)
2-(3-(4-(7H-[4,7'-Bipyrrolo[2,3-d]pyrimidin]-4'-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile
- CAS
- 2910813-45-3
- Formula
- C22H20N10O2S
- MW
- 488.5 g/mol
VQ-044448
![4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine chemical structure](/media/structures/YWBDBLXIRAQZIH-UHFFFAOYSA-N.svg)
4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine
- CAS
- 941685-26-3
- Formula
- C12H18ClN3OSi
- MW
- 283.83 g/mol
VQ-027953
6-Amino-5-(2,2-diethoxyethyl)-4-hydroxypyrimidine
- CAS
- 7400-06-8
- Formula
- C10H17N3O3
- MW
- 227.26 g/mol
VQ-035912
6-Amino-5(2,2-diethoxyethyl)-4-hydroxy-2-mercaptopyrimidine
- CAS
- 7400-05-7
- Formula
- C10H17N3O3S
- MW
- 259.33 g/mol
VQ-035911
Baricitinib-D4 (azetidine-2,2-d2)(Ethyl-1,1-d2)
- CAS
- 1564241-55-9
- Formula
- C16H13D4N7O2S
- MW
- 375.4 g/mol
VQ-045381
![N-((3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-5-oxotetrahydrofuran-3-yl)methyl)ethanesulfonamide chemical structure](/media/structures/CHCYTHXXIZXFQF-UHFFFAOYSA-N.svg)
N-((3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-5-oxotetrahydrofuran-3-yl)methyl)ethanesulfonamide
- CAS
- 2910813-43-1
- Formula
- C16H18N6O4S
- MW
- 390.4 g/mol
VQ-021736
tert-Butyl 3-(cyanomethyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)azetidine-1-carboxylate
- CAS
- 1153949-15-5
- Formula
- C19H29BN4O4
- MW
- 388.3 g/mol
VQ-035396
Tert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate
- CAS
- 1153949-11-1
- Formula
- C10H14N2O2
- MW
- 194.23 g/mol
VQ-044718
![Tert-Butyl 4-(1-(3-(cyanomethyl)-1-(ethylsulfonyl)azetidin-3-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate chemical structure](/media/structures/DSHUYPHBSXAOSA-UHFFFAOYSA-N.svg)
Tert-Butyl 4-(1-(3-(cyanomethyl)-1-(ethylsulfonyl)azetidin-3-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate
- CAS
- 2055723-13-0
- Formula
- C21H25N7O4S
- MW
- 471.5 g/mol
VQ-024497
![tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate chemical structure](/media/structures/XGGUTWYJGILAOA-UHFFFAOYSA-N.svg)
tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate
- CAS
- 1236033-21-8
- Formula
- C11H12ClN3O2
- MW
- 253.68 g/mol
VQ-029355
FAQs — Baricitinib impurities
Which Baricitinib impurities do you supply?
We list 46 Baricitinib-related reference materials, including process impurities, degradation products, nitrosamine impurities, stable-isotope-labelled standards and related compounds. Each is supplied with a COA, and characterisation data (HPLC, 1H-NMR, MS, IR) can be provided on request.
What are Baricitinib impurity standards used for?
They are used for analytical method development and validation, impurity identification and quantification, forced-degradation and stability studies, and to support ANDA, DMF and other regulatory submissions under ICH Q3A/Q3B (and ICH M7 for mutagenic impurities).
Can you synthesise a Baricitinib impurity that is not listed?
Yes. Our custom synthesis service can prepare and characterise unlisted impurities, metabolites and labelled analogues from milligram to gram scale. Share the structure or name and required quantity for a quotation.
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