tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidi… 1236033-21-8

Name: tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate
Brand: Vaqora Chemicals
SKU: VQ-029355

About tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate

Listed under CAS 1236033-21-8, tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate is an impurity of Baricitinib available from Vaqora Chemicals. With the molecular formula C11H12ClN3O2, it has a molar mass of 253.68 g/mol. Its systematic (IUPAC) name is tert-butyl 4-chloropyrrolo[2,3-d]pyrimidine-7-carboxylate. Common synonyms include chloro-, 1,1-dimethylethyl ester and 7-Boc-4-chloro-7H-pyrrolo[2,3-d]pyrimidine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Baricitinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Baricitinib

View every impurity, metabolite and intermediate we list for Baricitinib.

Baricitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate
Catalogue No.	VQ-029355
CAS Number	1236033-21-8
IUPAC name	tert-butyl 4-chloropyrrolo[2,3-d]pyrimidine-7-carboxylate
Molecular formula	C₁₁H₁₂ClN₃O₂
Molecular weight	253.68 g/mol
Exact mass	253.0618
Grade	Reference Standard
HSN code	38229090
InChIKey	XGGUTWYJGILAOA-UHFFFAOYSA-N
SMILES	CC(C)(C)OC(=O)N1C=CC2=C1N=CN=C2Cl
PubChem CID	59420184

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	0 / 4
TPSA	57 Å²
Synonyms	t-Butyl 4-chloropyrrolo[2,3-d]pyrimidine-7-carboxylate, 4-Chloro-7h-pyrrolo[2,3-d]pyrimidine-7-carboxylic acid 1,1-dimethylethyl ester, 7H-Pyrrolo[2,3-d]pyrimidine-7-carboxylic acid, 4- chloro-, 1,1-dimethylethyl ester, chloro-, 1,1-dimethylethyl ester, 7-Boc-4-chloro-7H-pyrrolo[2,3-d]pyrimidine, 7H-Pyrrolo[2,3-d]pyrimidine-7-carboxylic acid, 4-, ert-butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate, t-butyl 4-chloro-7h-pyrrolo[2,3-d]pyrimidine-7-carboxylate, 4-Chloro-pyrrolo[2,3-d]pyrimidine-7-carboxylic acid t-butyl ester

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate?

The CAS Registry Number of tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate is 1236033-21-8. It is also known as t-Butyl 4-chloropyrrolo[2,3-d]pyrimidine-7-carboxylate, 4-Chloro-7h-pyrrolo[2,3-d]pyrimidine-7-carboxylic acid 1,1-dimethylethyl ester, 7H-Pyrrolo[2,3-d]pyrimidine-7-carboxylic acid, 4- chloro-, 1,1-dimethylethyl ester.

What is the molecular formula and molecular weight of tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate?

tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate has the molecular formula C11H12ClN3O2 and a molecular weight of 253.68 g/mol. Its IUPAC name is tert-butyl 4-chloropyrrolo[2,3-d]pyrimidine-7-carboxylate.

What is tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate used for?

tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate is supplied as a characterised reference material related to Baricitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate can I order?

We supply tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate?

Yes. Every lot of tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate be shipped internationally?

Yes. We export tert-Butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.