1-(3-Methylbenzyl)piperazine

Name: 1-(3-Methylbenzyl)piperazine
Brand: Vaqora Chemicals
SKU: VQ-031758

About 1-(3-Methylbenzyl)piperazine

Vaqora Chemicals supplies 1-(3-Methylbenzyl)piperazine, an impurity of Meclizine registered under CAS number 5321-48-2. With the molecular formula C12H18N2, it has a molar mass of 190.28 g/mol. Systematically, it is named 1-[(3-methylphenyl)methyl]piperazine. Alternative names: Piperazine, 1-(m-methylbenzyl)- and 3-Methylbenzylpiperazine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Meclizine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1-(3-Methylbenzyl)piperazine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Meclizine

View every impurity, metabolite and intermediate we list for Meclizine.

Meclizine impurities

Specifications & identifiers

Chemical identifiers
Product name	1-(3-Methylbenzyl)piperazine
Catalogue No.	VQ-031758
CAS Number	5321-48-2
IUPAC name	1-[(3-methylphenyl)methyl]piperazine
Molecular formula	C₁₂H₁₈N₂
Molecular weight	190.28 g/mol
Exact mass	190.147
Grade	Reference Standard
HSN code	38229090
InChIKey	VTEOTZPEMDQENX-UHFFFAOYSA-N
SMILES	CC1=CC(=CC=C1)CN2CCNCC2
PubChem CID	79213

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	1 / 2
TPSA	15.3 Å²
Synonyms	Piperazine, 1-(m-methylbenzyl)-, 3-Methylbenzylpiperazine, 3-ME-BZP, Piperazine, 1-[(3-methylphenyl)methyl]-, Piperazine, 1-((3-methylphenyl)methyl)-, 1-(m-Methylbenzyl)piperazine, [(3-methylphenyl)methyl]piperazine, 1-m-Methylbenzylpiperazine, 1-(m-tolylmethyl)piperazine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-(3-Methylbenzyl)piperazine?

The CAS Registry Number of 1-(3-Methylbenzyl)piperazine is 5321-48-2. It is also known as Piperazine, 1-(m-methylbenzyl)-, 3-Methylbenzylpiperazine, 3-ME-BZP.

What is the molecular formula and molecular weight of 1-(3-Methylbenzyl)piperazine?

1-(3-Methylbenzyl)piperazine has the molecular formula C12H18N2 and a molecular weight of 190.28 g/mol. Its IUPAC name is 1-[(3-methylphenyl)methyl]piperazine.

What is 1-(3-Methylbenzyl)piperazine used for?

1-(3-Methylbenzyl)piperazine is supplied as a characterised reference material related to Meclizine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-(3-Methylbenzyl)piperazine can I order?

We supply 1-(3-Methylbenzyl)piperazine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-(3-Methylbenzyl)piperazine?

Yes. Every lot of 1-(3-Methylbenzyl)piperazine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-(3-Methylbenzyl)piperazine be shipped internationally?

Yes. 1-(3-Methylbenzyl)piperazine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.