Meclizine-D8 Dihydrochloride

Name: Meclizine-D8 Dihydrochloride
Brand: Vaqora Chemicals
SKU: VQ-038272

About Meclizine-D8 Dihydrochloride

Listed under CAS 1246816-06-7, Meclizine-D8 Dihydrochloride is a stable isotope labelled analogue related to Meclizine available from Vaqora Chemicals. Formula C25H27ClN2, molecular weight 399.0 g/mol. Systematically, it is named 1-[(4-chlorophenyl)-phenylmethyl]-2,2,3,3,5,5,6,6-octadeuterio-4-[(3-methylphenyl)methyl]piperazine. Common synonyms include Meclizine D8.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Meclizine and related analytes in bioanalytical, pharmacokinetic and impurity studies. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Meclizine-D8 Dihydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Meclizine

View every impurity, metabolite and intermediate we list for Meclizine.

Meclizine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Meclizine-D8 Dihydrochloride
Catalogue No.	VQ-038272
CAS Number	1246816-06-7
IUPAC name	1-[(4-chlorophenyl)-phenylmethyl]-2,2,3,3,5,5,6,6-octadeuterio-4-[(3-methylphenyl)methyl]piperazine
Molecular formula	C₂₅H₂₇ClN₂
Molecular weight	399 g/mol
Exact mass	398.2365
Grade	Reference Standard
HSN code	38229090
InChIKey	OCJYIGYOJCODJL-AZGHYOHESA-N
SMILES	[2H]C1(C(N(C(C(N1CC2=CC=CC(=C2)C)([2H])[2H])([2H])[2H])C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl)([2H])[2H])[2H]
PubChem CID	57369287

Physical properties
Physical form	Solid
LogP (XLogP3)	5.8
H-bond donors / acceptors	0 / 2
TPSA	6.5 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Meclizine-D8 Dihydrochloride?

The CAS Registry Number of Meclizine-D8 Dihydrochloride is 1246816-06-7. It is also known as Meclizine D8.

What is the molecular formula and molecular weight of Meclizine-D8 Dihydrochloride?

Meclizine-D8 Dihydrochloride has the molecular formula C25H27ClN2 and a molecular weight of 399 g/mol. Its IUPAC name is 1-[(4-chlorophenyl)-phenylmethyl]-2,2,3,3,5,5,6,6-octadeuterio-4-[(3-methylphenyl)methyl]piperazine.

What is Meclizine-D8 Dihydrochloride used for?

Meclizine-D8 Dihydrochloride is supplied as a characterised reference material related to Meclizine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Meclizine-D8 Dihydrochloride can I order?

We supply Meclizine-D8 Dihydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Meclizine-D8 Dihydrochloride?

Yes. Every lot of Meclizine-D8 Dihydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Meclizine-D8 Dihydrochloride be shipped internationally?

Yes. We export Meclizine-D8 Dihydrochloride worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.