1-Hydroxy Dapagliflozin Impurity

Name: 1-Hydroxy Dapagliflozin Impurity
Brand: Vaqora Chemicals
SKU: VQ-004289

About 1-Hydroxy Dapagliflozin Impurity

Listed under CAS 461432-27-9, 1-Hydroxy Dapagliflozin Impurity is an impurity of Dapagliflozin available from Vaqora Chemicals. Formula C21H25ClO7, molecular weight 424.9 g/mol. The IUPAC name is (3R,4S,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-2,3,4,5-tetrol. Common synonyms include Dapagliflozin Impurity B.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Dapagliflozin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1-Hydroxy Dapagliflozin Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dapagliflozin

View every impurity, metabolite and intermediate we list for Dapagliflozin.

Dapagliflozin impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Hydroxy Dapagliflozin Impurity
Catalogue No.	VQ-004289
CAS Number	461432-27-9
IUPAC name	(3R,4S,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
Molecular formula	C₂₁H₂₅ClO₇
Molecular weight	424.9 g/mol
Exact mass	424.1289
Grade	Reference Standard
HSN code	38229090
InChIKey	KYDGWGYAUCJZDV-AWGDKMGJSA-N
SMILES	CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C3([C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)Cl
PubChem CID	10342331

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	5 / 7
TPSA	120 Å²
Synonyms	1-C-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose, Dapagliflozin Impurity B, D-Glucopyranose, 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, 1-C-{4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-D-glucopyranose, 1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose, 1-?C-?[4-?Chloro-?3-?[(4-?ethoxyphenyl)?methyl]?phenyl]?-D-?Glucopyranose

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Hydroxy Dapagliflozin Impurity?

The CAS Registry Number of 1-Hydroxy Dapagliflozin Impurity is 461432-27-9. It is also known as 1-C-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose, Dapagliflozin Impurity B, D-Glucopyranose, 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-.

What is the molecular formula and molecular weight of 1-Hydroxy Dapagliflozin Impurity?

1-Hydroxy Dapagliflozin Impurity has the molecular formula C21H25ClO7 and a molecular weight of 424.9 g/mol. Its IUPAC name is (3R,4S,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-2,3,4,5-tetrol.

What is 1-Hydroxy Dapagliflozin Impurity used for?

1-Hydroxy Dapagliflozin Impurity is supplied as a characterised reference material related to Dapagliflozin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Hydroxy Dapagliflozin Impurity can I order?

We supply 1-Hydroxy Dapagliflozin Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Hydroxy Dapagliflozin Impurity?

Yes. Every lot of 1-Hydroxy Dapagliflozin Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Hydroxy Dapagliflozin Impurity be shipped internationally?

Yes. We export 1-Hydroxy Dapagliflozin Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.